Who is sponsoring NCT06192472?

NCT06192472 is sponsored by University of Surrey.

What condition does NCT06192472 study?

NCT06192472 studies Varicose Veins.

What drugs are being tested in NCT06192472?

Interventions: Chemical sclerotherapy, 1% Sodium Tetradecyl Sulphate, 3% Sodium Tetradecyl Sulphate, 0.5% Polidocanol, 3% Polidcanol.

What is the status of NCT06192472?

NCT06192472 is currently COMPLETED.

Last reviewed 2024-01-03 · How we verify

Investigation Into the Pathophysiology and Treatment of Varicose Veins

NCT06192472 NA COMPLETED

Chemical sclerotherapy is commonly used to treat varicose veins which affect superficial veins in the leg. Sclerotherapy is injected directly into veins where it causes damage to the vein wall. If sufficient damage occurs, the vein is transformed into a fibrous cord which does not re-open. This study will investigate the structural changes caused to the wall of veins following injection with sclerotherapy ex vivo. Vein samples will be obtained from the Whiteley Clinic in Guildford from patients undergoing phlebectomy operations. These will then be injected with sclerotherapy and the extent of damage will be investigated. Samples will also be used for laboratory analysis into the pathophysiology of varicose veins.

Details

Lead sponsor	University of Surrey
Phase	NA
Status	COMPLETED
Enrolment	120
Start date	2013-04
Completion	2015-09

Conditions

Varicose Veins

Interventions

Chemical sclerotherapy
1% Sodium Tetradecyl Sulphate
3% Sodium Tetradecyl Sulphate
0.5% Polidocanol
3% Polidcanol

Primary outcomes

To identify the mechanisms responsible for the therapeutic effects of sclerotherapy in varicose veins. — 2 years 4 months
no additional details - project ended 2015 and staff have left

Countries

United Kingdom