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NCT06181474: MELDESAS
MELD ESAS Evolution: Assessment of the Symptomatic Burden of Patients With Advanced Chronic Liver Disease
trial testing ESAS in Palliative Care in 44 participants. Completed in 25 January 2025.
31 December 2024
Quick facts
| Lead sponsor | Unidade Local de Saúde de Matosinhos, EPE |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 44 |
| Start date | 1 January 2024 |
| Primary completion | 31 December 2024 |
| Estimated completion | 25 January 2025 |
| Sites | 1 location across Portugal |
Drugs / interventions tested
- ESAS
Conditions studied
- Palliative Care — all drugs for Palliative Care →
- End Stage Liver DIsease — all drugs for End Stage Liver DIsease →
Sponsor
Unidade Local de Saúde de Matosinhos, EPE
Who can join
18 and older, any sex, with Palliative Care or End Stage Liver DIsease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this observational study is to understand if there is a correlation between the evolution of MELD-Na and symptomatic burden of patients with advanced chronic liver disease. All patients with chronic liver disease will be invited to participate in the study. Patients will be followed prospectively with assessment of their MELD-Na score and symptom burden, according to the Edmonton Symptom Assessment System scale.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Symptom burden in end-stage liver disease: a prospective cohort study of the symptoms experienced by patients and the role of palliative care.
Oliveira HM, Ribeiro F, Lopes G, Frias E, et al · · 2025 · PMID 40661221 · DOI 10.1177/17562848251353624
Verify or expand the search:
- PubMed search for NCT06181474
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Unidade Local de Saúde de Matosinhos, EPE trials
Trials by the same sponsor.
- NCT04828941 — My Healthy Diary - An Electronic Diary for Remote Migraine Monitoring · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06181474 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Unidade Local de Saúde de Matosinhos, EPE
- Last refreshed: 4 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06181474.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing