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NCT06181279
Effects of Individualized PEEP Guided by Driving Pressure on Postoperative Atelectasis in Patients With Morbid Obesity
NA trial testing Individualized PEEP group in Pulmonary Atelectasis in 52 participants. Currently enrolling.
31 December 2024
Quick facts
| Lead sponsor | Yongtao Sun |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 52 |
| Start date | 1 March 2024 |
| Primary completion | 31 December 2024 |
| Estimated completion | 31 December 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- Individualized PEEP group
- Fixed PEEP group
Conditions studied
- Pulmonary Atelectasis — all drugs for Pulmonary Atelectasis →
- Obesity, Morbid — all drugs for Obesity, Morbid →
Sponsor
Yongtao Sun — full company profile →
Who can join
Adults 18 to 60, any sex, with Pulmonary Atelectasis or Obesity, Morbid. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Atelectasis is a common complication in patients undergoing surgery under general anesthesia, particularly in obese patients. Postoperative atelectasis could last for more than 24h and contribute to a variety of other complications, including hypoxemia and pneumonia. We plan to conduct a single-center, randomized controlled trial in patients undergoing bariatric surgery to test the hypothesis that driving pressure guided PEEP could reduce the postoperative atelectasis.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of driving pressure-guided individualised positive end-expiratory pressure on postoperative atelectasis in patients with morbid obesity: study protocol of a randomised controlled trial.
Ren Y, Sun YT, Zhang P, Chen L, et al · · 2025 · PMID 40050061 · DOI 10.1136/bmjopen-2024-091217
Verify or expand the search:
- PubMed search for NCT06181279
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Pulmonary Atelectasis
Currently open trials in the same condition.
- NCT06824506 — Ultrasound for Postop Lung Issues in Low-Flow Anesthesia · recruiting
Other Yongtao Sun trials
Trials by the same sponsor.
- NCT07477951 — The Impact of Automatic Lung Recruitment Postoperative Pulmonary Complications · NA · not yet recruiting
- NCT06953570 — Impact of Frailty on Nalbuphine Dose for Postoperative Analgesia in Elderly Patients Undergoing Laparoscopic GI Surgery · not yet recruiting
- NCT06712199 — Effect of Oxalidine Combined with Reduced-opioid Anesthesia on Multimodal Analgesia in Morbidly Obese Patients Undergoin · Phase 4 · not yet recruiting
- NCT06165991 — Liposomal and Standard Bupivacaine in Thoracic Paravertebral Block for Post-Thoracoscopic Pain · Phase 4 · recruiting
- NCT05635877 — Effects of Low-dose Esmolol on Myocardial Injury After Non-cardiac Surgery in Elderly Frail Patients · Phase 4 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06181279 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yongtao Sun
- Last refreshed: 4 June 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06181279.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing