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NCT06181019: ACWMITTOOAB

Acupuncture Combined With Mirabegron in the Treatment of OAB

Status unknown Phase 1 Last updated 26 December 2023
What this trial tests

Phase 1 trial testing 50 mg of mirabegron in Overactive Bladder in 75 participants. Status unknown.

Timeline
1 December 2021
Primary endpoint
31 March 2023
31 December 2024

Quick facts

Lead sponsorThe Affiliated Ganzhou Hospital of Nanchang University
PhasePhase 1
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingquadruple
Primary purposetreatment
Enrollment75
Start date1 December 2021
Primary completion31 March 2023
Estimated completion31 December 2024
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

The Affiliated Ganzhou Hospital of Nanchang University

Who can join

Adults 14 to 75, any sex, with Overactive Bladder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Introduction: As conventional treatments for overactive bladder (OAB) have not yet shown satisfactory results, new approaches are needed. Therefore, this study aimed to investigate the efficacy and safety of acupuncture combined with mirabegron for the treatment of OAB. Methods: This prospective cohort study enrolled 80 OAB patients who were then divided into control and treatment groups using a randomized number-table method. The control group was administered mirabegron alone (50 mg/day), while the treatment group was administered mirabegron orally along with acupuncture at the following points: guanyuan (CV4), zhongji (CV3), and sanyinjiao (SP6). The OAB symptom score (overactive bladder syndrome score \[OABSS\]), voiding, urgency, nocturia, incontinence, and incidence of related adverse events were compared between the two groups at baseline and after 4, 8, and 12 weeks of treatment.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Currently open trials in the same condition.

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