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NCT06180876: RED
Effect of Remimazolam on Postoperative Delirium
NA trial testing remimazolam in General Anesthetic Drug Adverse Reaction in 264 participants. Completed in 30 January 2024.
25 January 2024
Quick facts
| Lead sponsor | Zhihong LU |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 264 |
| Start date | 25 July 2022 |
| Primary completion | 25 January 2024 |
| Estimated completion | 30 January 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- remimazolam — full drug profile →
- propofol (Propofol) — full drug profile →
Conditions studied
- General Anesthetic Drug Adverse Reaction — all drugs for General Anesthetic Drug Adverse Reaction →
Sponsor
Zhihong LU — full company profile →
Who can join
60 and older, any sex, with General Anesthetic Drug Adverse Reaction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Remimazolam is a novel benzodiazepine with ultra-short onset and offset of its effect. It can be used for general anesthesia. However, classical benzodiazepine such as midazolam was reported to increase the risk of postoperative delirium. Thus, the investigators aim to investigate the effect of remimazolam general anesthesia on postoperative delirium in elderly patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06180876
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of remimazolam
Trials testing the same drug.
- NCT06093971 — Remimazolam Versus Propofol for General Anesthesia Induction in Patients on Renin-angiotensin System Blockers Undergoing · NA · completed
- NCT05485064 — Moderate Sedation Combined With Acupuncture Anesthesia in Gastroscopy and Colonoscopy on Screening Research · NA · completed
- NCT05164146 — The Comparison of Hypotension Incidence Between Remimazolam and Propofol in Hypertensive Patients Undergoing Neurosurger · NA · completed
- NCT04950621 — Remimazolam and Endovascular Procedures of Cerebrovascular Diseases · NA · completed
Other recruiting trials for General Anesthetic Drug Adverse Reaction
Currently open trials in the same condition.
- NCT07323043 — Comparison of Cough Response Between Tegilidine and Sufentanil as Pre-induction Agents in General Anesthesia · NA · recruiting
- NCT07287683 — Evaluation of Postoperative Pain in Cases Undergoing Cataract Surgery Under Topical Versus General Anesthesia · Phase 1, PHASE2 · active not recruiting
- NCT06707532 — The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA) · NA · recruiting
- NCT06216002 — Incidence of Residual Neuromuscular Blockade in Fraility in OncoGynae Surgery · NA · recruiting
Other Zhihong LU trials
Trials by the same sponsor.
- NCT07440121 — Optimized Strict Fluid Management Helps Improve Endpoints After Liver Dissection · NA · not yet recruiting
- NCT07445399 — Drawing Therapy for pReoperative Anxiety in Waiting (DRAW) · NA · not yet recruiting
- NCT07433218 — Frequency of Electrical Acupoint Stimulation on Hypotension During Induction · NA · not yet recruiting
- NCT06521632 — Acupoint Stimulation Improves Cognition Under Hypoxia · NA · not yet recruiting
- NCT06161662 — STimulation Electronically of Acupoints for Postoperative Delirium in elderlY Patients · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06180876 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Zhihong LU
- Last refreshed: 23 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06180876.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing