Last reviewed · How we verify
NCT06179771: HACEC
Pilot Study on HA380 Column Use in Critically Ill Patients Receiving Extracorporeal Support.
NA trial testing HA 380 in Acute Kidney Injury in 40 participants. Currently enrolling.
30 June 2026
Quick facts
| Lead sponsor | University Hospitals, Leicester |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 2 September 2024 |
| Primary completion | 30 June 2026 |
| Estimated completion | 31 October 2026 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- HA 380
Conditions studied
- Acute Kidney Injury — all drugs for Acute Kidney Injury →
- ARDS — all drugs for ARDS →
- Inflammation — all drugs for Inflammation →
- Extracorporeal Circulation; Complications — all drugs for Extracorporeal Circulation; Complications →
Sponsor
University Hospitals, Leicester
Who can join
Adults 18 to 65, any sex, with Acute Kidney Injury or ARDS. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients who are very ill either due to a severe infection, major organ injury, trauma or a major operation may require significant support with devices such as a dialysis machine for the kidneys or Extracorporeal Membrane Oxygenation (ECMO) for the heart and lungs. This is often due to a reaction of the body to the insult which is termed inflammation. The investigators would like to assess if the use of a device that can remove the agents driving this reaction can lead to a quicker recovery form the illness. The device is a blood filter called HA380 and it would be connected to either the dialysis machine or the ECMO circuit. The investigators want to assess the feasibility of conducting a study with the HA380 column. We will also evaluate if the use of the HA380 column has an effect on the time spent on dialysis or ECMO, time spent on the breathing machine, time spent requiring drugs to support blood pressure and time spent in the intensive care unit.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06179771
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University Hospitals, Leicester trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06179771 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospitals, Leicester
- Last refreshed: 2 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06179771.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing