Last reviewed · How we verify
NCT06178874
Insulin Degludec vs Insulin Glargine for Glycemic Control in Critical Illness Hyperglycemia
NA trial testing Insulin Glargine in Glycemic Control in 90 participants. Completed in 1 June 2024.
25 May 2024
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 90 |
| Start date | 1 December 2023 |
| Primary completion | 25 May 2024 |
| Estimated completion | 1 June 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Insulin Glargine (INSULIN GLARGINE) — full drug profile →
- Insulin Degludec (INSULIN DEGLUDEC) — full drug profile →
- Insulin regular — full drug profile →
Conditions studied
- Glycemic Control — all drugs for Glycemic Control →
- Insulin — all drugs for Insulin →
- Critical Illness — all drugs for Critical Illness →
Sponsor
Ain Shams University
Who can join
Adults 18 to 60, any sex, with Glycemic Control or Insulin. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The role of ultralong insulin in the control of the blood glucose level in diabetic patients is well known, the current study will discuss the role of ultralong insulin in controlling of hyperglycaemia in critical illness defined as failure or impending failure of an organ
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Insulin Degludec vs Insulin Glargine for Glycemic Control in Critical Illness Hyperglycemia.
El Sherif IM, Haggag AM, Abbas MH, Kamel WY. · · 2025 · PMID 39802245 · DOI 10.5005/jp-journals-10071-24842
Verify or expand the search:
- PubMed search for NCT06178874
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Insulin Glargine
Trials testing the same drug.
- NCT06370715 — A Study of LY900014 in Adult Participants With Type 2 Diabetes Mellitus in India · Phase 4 · completed
- NCT05803421 — A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and O · Phase 3 · completed
- NCT05699408 — To Compare the Efficacy and Safety of INS068 and Insulin Glargine in Subjects With Type 2 Diabetes Mellitus Not Adequate · Phase 3 · completed
- NCT05702073 — To Compare the Efficacy and Safety of INS068 and Insulin Glargine in Subjects With Type 2 Diabetes Mellitus Treated With · Phase 3 · completed
- NCT05614089 — Human Versus Analogue Insulin for Youth With Type 1 Diabetes in Low-Resource Settings · Phase 4 · completed
Other recruiting trials for Glycemic Control
Currently open trials in the same condition.
- NCT06817252 — How a Mediterranean Diet With Potatoes Impacts Heart and Metabolic Health in Adults With Pre-Diabetes · NA · recruiting
- NCT06810596 — Comparing Efficacy Between Two Protocols of Intravenous Insulin Infusion for Diabetic Adults in ICU · NA · recruiting
- NCT05644717 — Effect of Erugliflozin On Liver Fat, Liver Fibrosis and Glycemic Control in Type II DM Patients With NASH/NAFLD · Phase 4 · recruiting
Other Ain Shams University trials
Trials by the same sponsor.
- NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
- NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
- NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
- NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
- NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06178874 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 5 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06178874.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing