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NCT06170073: HK-ASAP
Hong Kong Cohort of Abnormal Sleep in Ageing Population (HK-ASAP): Focusing on Brain Health and Sleep Quality
trial in Sleep Disturbance in 238 participants. Completed in 10 January 2025.
31 December 2024
Quick facts
| Lead sponsor | Chinese University of Hong Kong |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 238 |
| Start date | 1 October 2023 |
| Primary completion | 31 December 2024 |
| Estimated completion | 10 January 2025 |
| Sites | 1 location across Hong Kong |
Conditions studied
- Sleep Disturbance — all drugs for Sleep Disturbance →
- Aging — all drugs for Aging →
- Cognitive Decline — all drugs for Cognitive Decline →
- Brain Disease — all drugs for Brain Disease →
Sponsor
Chinese University of Hong Kong
Who can join
Adults 55 to 95, any sex, with Sleep Disturbance or Aging. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Poor sleep quality can significantly jeopardize the brain health, cognitive functions, daily activities, quality of life, and even be implicated as a key potential contributing factor in the development of accelerated cognitive decline and prodromal dementia. Consequently, research efforts to understand, and therefore potentially model, the effects of sleep quality on cognition and brain health are of great pragmatic values.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Focused low-intensity hippocampal transcranial ultrasound stimulation (TUS) for sleep disturbances in patients with chronic tinnitus: A study protocol for a pilot randomized controlled trial.
Ni X, Yuen YS, Li Z, Wang K, et al · · 2025 · cited 2× · PMID 40768410 · DOI 10.1371/journal.pone.0329950 -
Daily high-frequency transcranial random noise stimulation (hf-tRNS) for sleep disturbances and cognitive dysfunction in patients with mild vascular cognitive impairments: A study protocol for a pilot randomized controlled trial.
Gong Y, Li J, Yuen YS, Yang NS, et al · · 2024 · cited 2× · PMID 39441802 · DOI 10.1371/journal.pone.0309233 -
HK-ASAP study: protocol for a prospective cohort study on sleep quality, brain reserve and cognitive phenotypes in community-dwelling older adults.
Ni X, Yang NS, Yuen YS, Gong Y, et al · · 2026 · PMID 41882580 · DOI 10.1186/s12877-026-07367-0
Verify or expand the search:
- PubMed search for NCT06170073
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Chinese University of Hong Kong trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06170073 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chinese University of Hong Kong
- Last refreshed: 14 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06170073.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing