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Exploring Biomarkers for Therapeutic Response of Lupus Nephritis Based on Multi Omics Analysis
This is an observational study of patients with lupus nephritis aiming to find biomarkers that can predict patients' response to immunosuppressants. We planed to collect 100 lupus nephritis patients' peripheral blood,kidney tissues and urine before and after treatment (mycophenolate mofetil or cyclophosphamide, in combination with glucocorticoids). Then multi omics analysis, including single cell RNA-seq, ATAC-seq and CITE-seq, will be performed to find new biomarkers for patients' response and prognosis.
Details
| Lead sponsor | Chinese SLE Treatment And Research Group |
|---|---|
| Status | RECRUITING |
| Enrolment | 100 |
| Start date | Tue Dec 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Tue Dec 05 2028 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Lupus Nephritis
Countries
China