NCT06164418 is a NA clinical trial of Dental restoration in Secondary Caries, sponsored by Mansoura University.

Who is sponsoring NCT06164418?

NCT06164418 is sponsored by Mansoura University.

What drugs are being tested in NCT06164418?

Interventions in NCT06164418: Dental restoration.

What condition does NCT06164418 study?

NCT06164418 studies Secondary Caries, Dental Restoration Failure of Marginal Integrity.

Is NCT06164418 still recruiting?

NCT06164418 is currently active, enrolled. Last updated 3 June 2025.

Last reviewed 2025-06-03 · How we verify

NCT06164418

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparative Evaluation of Class V Restorations

Active, enrolled NA Last updated 3 June 2025

What this trial tests

NA trial testing Dental restoration in Secondary Caries in 100 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

2 December 2023

Primary endpoint
2 December 2025

15 December 2025

Quick facts

Lead sponsor	Mansoura University
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	100
Start date	2 December 2023
Primary completion	2 December 2025
Estimated completion	15 December 2025
Sites	1 location across Egypt

Drugs / interventions tested

Dental restoration

Conditions studied

Secondary Caries — all drugs for Secondary Caries →
Dental Restoration Failure of Marginal Integrity — all drugs for Dental Restoration Failure of Marginal Integrity →

Sponsor

Mansoura University

Who can join

Adults 35 to 50, any sex, with Secondary Caries or Dental Restoration Failure of Marginal Integrity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To evaluate and compare the 2-year clinical performance of Class V restorations using various restorative systems with ion-releasing and non-ion-releasing composites, utilizing fluoride-free and fluoride-releasing universal adhesives for bonding

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

A two-year randomized clinical trial of bulk-fill and ion-releasing composites with universal adhesives in class V carious lesions.
Ismail HS, Soliman HAN, Ali AI, Raghip AG, et al · · 2026 · PMID 41964796 · DOI 10.1007/s00784-026-06852-5

Verify or expand the search:

Other trials of Dental restoration

Trials testing the same drug.

NCT06543680 — Resin Modified Glass Ionomer Versus Self-Adhesive Resin Composite Restorative Systems · NA · recruiting
NCT05583682 — Clinical Performance of Resin-modified Glass Ionomer and Composite Restorations in Permanent Teeth · NA · completed

Other recruiting trials for Secondary Caries

Currently open trials in the same condition.

NCT03108586 — Caries Cognition and Identification in Adults · NA · active not recruiting

Other Mansoura University trials

Trials by the same sponsor.

NCT05785377 — Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia · NA · not yet recruiting
NCT07509567 — Conventional Palatal Crib Versus Bonded Spurs for Anterior Open Bite Treatment · NA · not yet recruiting
NCT07393178 — Efficacy & Safety of High Power vs. Low Power Holmium Laser in Mini-PCNL for Large Renal Stones · NA · not yet recruiting
NCT07436182 — Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. · Phase 4 · not yet recruiting
NCT07534943 — Effectiveness of Oleanolic Acid as Intracanal Medicament on Infectious/Inflammatory Contents in Teeth With Apical Period · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06164418 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mansoura University
Last refreshed: 3 June 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06164418.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing