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NCT06157424
Efficacy and Safety of Combined Thread Embedding Acupuncture With Auricular Acupuncture for GERD
NA trial testing Thread Embedding Acupuncture in GERD in 66 participants. Completed in 18 March 2024.
18 March 2024
Quick facts
| Lead sponsor | University of Medicine and Pharmacy at Ho Chi Minh City |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 66 |
| Start date | 6 December 2023 |
| Primary completion | 18 March 2024 |
| Estimated completion | 18 March 2024 |
| Sites | 1 location across Vietnam |
Drugs / interventions tested
- Thread Embedding Acupuncture
- Auricular acupuncture
- Standard treatment
Conditions studied
- GERD — all drugs for GERD →
Sponsor
University of Medicine and Pharmacy at Ho Chi Minh City
Who can join
Adults 18 to 60, any sex, with GERD. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Gastroesophageal reflux disease (GERD) is increasingly prevalent today. Proton-pump inhibitors (PPIs) are the primary treatment, yet their effectiveness remains limited. Various acupuncture methods have shown promise in treating GERD. Among these, thread embedding acupuncture (TEA) and auricular acupuncture (AA) offer the advantage of prolonged treatment per intervention, significantly reducing healthcare visits for procedures, particularly beneficial for conditions requiring extended therapy. This has led to the widespread application of TEA and AA in GERD treatment. However, evidence supporting their effectiveness remains inconclusive. In this study, we aim to assess the efficacy and safety of combining TEA with AA for treating GERD. According to traditional medicine, treatment should be pattern-based. Thus, we will focus on patients exhibiting the Liver Qi Invading Stomach pattern, as reports indicate its prevalence among GERD patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Systematic mapping of registered interventional studies addressing the top 10 research priorities in Barrett's oesophagus and gastro-oesophageal reflux disease.
Gamakaranage C, Ratcliffe E, Britton J, Butler T, et al · · 2025 · PMID 40527525 · DOI 10.1136/bmjgast-2025-001738
Verify or expand the search:
- PubMed search for NCT06157424
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for GERD
Currently open trials in the same condition.
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Other University of Medicine and Pharmacy at Ho Chi Minh City trials
Trials by the same sponsor.
- NCT07530042 — Efficacy of Electroacupuncture Combined With Auricular Acupressure for Chronic Low Back Pain. · NA · not yet recruiting
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- NCT07520071 — "Xuong Tan Lac Than" Exercise for Range of Motion and Muscle Endurance · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06157424 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Medicine and Pharmacy at Ho Chi Minh City
- Last refreshed: 20 March 2024
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