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NCT06157073: AVAC
Efficacy and Safety of Automated Closed-loop Ventilator vs Conventional Open-loop Ventilator in the Emergency Department
NA trial testing Closed-loop ventilator in Ventilator Lung in 132 participants. Status unknown.
31 December 2024
Quick facts
| Lead sponsor | University of Malaya |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 132 |
| Start date | 1 January 2024 |
| Primary completion | 31 December 2024 |
| Estimated completion | 31 December 2025 |
Drugs / interventions tested
- Closed-loop ventilator
- Open-loop ventilator
Conditions studied
- Ventilator Lung — all drugs for Ventilator Lung →
- Mechanical Ventilation Complication — all drugs for Mechanical Ventilation Complication →
- Ventilator-Induced Lung Injury — all drugs for Ventilator-Induced Lung Injury →
- ARDS — all drugs for ARDS →
Sponsor
University of Malaya
Who can join
18 and older, any sex, with Ventilator Lung or Mechanical Ventilation Complication. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients presenting to the emergency department (ED) may require breathing support with machines depending on the condition. Throughout the breathing support, the settings on the breathing machines will be tailored to the patient's requirements. These settings are manually adjusted by trained physicians. Currently, there are machines which can automatically change the settings based on real-time specific information obtained from the patient. This study aims to compare the use of machines which require manual adjustments (open-loop conventional ventilators) and machines which can automatically change the settings (closed-loop automated ventilators). Patients will be carefully selected to ensure no harm is caused whilst delivering the best care. This study will look into the duration when patients are receiving optimum settings and levels of oxygen and carbon dioxide in the blood. The outcomes of this study would allow us to identify methods to improve patient care.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06157073
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Ventilator Lung
Currently open trials in the same condition.
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- NCT05875883 — Phrenic Identification in the ICU · active not recruiting
- NCT06361420 — Driving Pressure-guided Lung Protective Ventilation · NA · recruiting
- NCT06483529 — Respiratory Mechanics Measurement of Ventilated Patients Through Low-frequency Oscillometry Technique · NA · recruiting
Other University of Malaya trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06157073 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Malaya
- Last refreshed: 5 December 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06157073.
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