Last reviewed · How we verify
NCT06155838
Reducing Depression and Anxiety Among Teens
NA trial testing "Early Adolescent Skills for Emotions (EASE) in Anxiety in 450 participants. Completed in 31 March 2024.
31 March 2024
Quick facts
| Lead sponsor | Aga Khan University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 450 |
| Start date | 27 November 2023 |
| Primary completion | 31 March 2024 |
| Estimated completion | 31 March 2024 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- "Early Adolescent Skills for Emotions (EASE)
Conditions studied
- Anxiety — all drugs for Anxiety →
- Depression — all drugs for Depression →
Sponsor
Aga Khan University
Who can join
Adults 13 to 19, any sex, with Anxiety or Depression. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this clinical trial is to assess the efficacy of the Early Adolescent Skills for Emotions (EASE) program, a school-based, non-specialist psychosocial intervention developed by the WHO for LMICs, in alleviating Anxiety and Depression among teens aged 13-19. The primary inquiries it seeks to address include: Does the EASE intervention effectively reduce anxiety and depression scores 12 weeks after implementation? * Can the EASE intervention enhance quality of life, improve problem-solving skills, and increase perceived emotional support? * Is the EASE intervention beneficial for enhancing the psychological well-being of parents and fostering positive parent-teen relationships?
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
To evaluate the EASE intervention for reducing anxiety and depression among adolescents in Pakistan: a protocol for a mixed methods study, including a cluster-randomised controlled trial.
Ghazal L, Cui N, Cao F. · · 2025 · cited 1× · PMID 40122537 · DOI 10.1136/bmjopen-2024-086393
Verify or expand the search:
- PubMed search for NCT06155838
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Anxiety
Currently open trials in the same condition.
- NCT07336238 — Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or · Phase 2 · recruiting
- NCT07522944 — AI-Guided Relaxation for Hemodialysis Anxiety · NA · recruiting
- NCT07466875 — Auricular Stimulation for Nicotine Withdrawal in Psychiatric Inpatients · NA · recruiting
- NCT07425951 — Building Cognitive Behavioural Skills With StoryBooks to Reduce Emotional Difficulties in Kindergarten Years · NA · recruiting
- NCT07473505 — Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospect · recruiting
Other Aga Khan University trials
Trials by the same sponsor.
- NCT07475793 — Image Guided Genicular Nerve Radiofrequency Ablation for Chronic Knee Osteoarthritis · NA · not yet recruiting
- NCT07197684 — Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surg · NA · not yet recruiting
- NCT07356063 — Self-Efficacy Enhancement Using a Multicomponent Support Group for Caregivers of Children With DMD/SMA · NA · not yet recruiting
- NCT07451951 — Effectiveness of SQLNS vs MQLNS for Prevention of Undernutrition in Children 6-12 Months · NA · not yet recruiting
- NCT07357350 — Effectiveness of Pain Management Interventions in Patients With Abdominal and Pelvic Cancer · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06155838 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aga Khan University
- Last refreshed: 3 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06155838.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing