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NCT06154551
Evaluation of the Levels of Salivary Paxillin Oral Premalignant and Malignant Lesions
trial testing Paxillin biomarker in Comparison of Salivary Paxillin Levels in OPMLs and OSCC to Healthy Subjects in 45 participants. Completed in 1 November 2023.
20 June 2023
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 45 |
| Start date | 29 November 2022 |
| Primary completion | 20 June 2023 |
| Estimated completion | 1 November 2023 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Paxillin biomarker
Conditions studied
- Comparison of Salivary Paxillin Levels in OPMLs and OSCC to Healthy Subjects — all drugs for Comparison of Salivary Paxillin Levels in OPMLs and OSCC to Healthy Subjects →
Sponsor
Cairo University
Who can join
Adults 30 to 70, any sex, with Comparison of Salivary Paxillin Levels in OPMLs and OSCC to Healthy Subjects. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This investigation was carried out to analyze and compare the salivary paxillin levels between oral premalignant and malignant lesions (OPMLs), OSCC and the healthy controls in order to assess its potential role as a biomarker of oral cancer aiming for early diagnosis and better prognosis of OSCC. Methods: Forty-five patients, ranging in age from thirty to seventy-five, were divided into three groups: fifteen patients with OPMLs (lichen planus, leukoplakia), fifteen patients with OSCC, and fifteen controls who were in general well. Paxillin was identified in saliva samples by using an ELISA kit.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Evaluation of the levels of salivary paxillin in oral potentially malignant disorders and malignant lesions.
Hussine AA, Selim K, Shaker O, Kamal Y. · · 2024 · cited 2× · PMID 39048985 · DOI 10.1186/s12903-024-04569-z
Verify or expand the search:
- PubMed search for NCT06154551
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06154551 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 4 December 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06154551.
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