Who is sponsoring NCT06153706?

NCT06153706 is sponsored by Yasmeen Khaled.

What condition does NCT06153706 study?

NCT06153706 studies Periodontitis.

Is NCT06153706 still recruiting?

NCT06153706 is currently completed. Last updated 1 December 2023.

Last reviewed 2023-12-01 · How we verify

NCT06153706

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of L-PRF as an Antibiotic Slow-release Biological Device in the Treatment of Moderate Periodontitis

Completed Phase 2, PHASE3 Last updated 1 December 2023

What this trial tests

Phase 2, PHASE3 trial testing Subgingival application of L-PRF loaded with metronidazole in Periodontitis in 24 participants. Completed in 1 October 2023.

Timeline

1 June 2022

Primary endpoint
1 October 2023

1 October 2023

Quick facts

Lead sponsor	Yasmeen Khaled
Phase	Phase 2, PHASE3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	24
Start date	1 June 2022
Primary completion	1 October 2023
Estimated completion	1 October 2023
Sites	1 location across Egypt

Drugs / interventions tested

Subgingival application of L-PRF loaded with metronidazole — full drug profile →
Subgingival application of L-PRF

Conditions studied

Periodontitis — all drugs for Periodontitis →

Sponsor

Yasmeen Khaled — full company profile →

Who can join

Adults 25 to 50, any sex, with Periodontitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aimed to evaluate the efficacy of leukocyte platelet-rich fibrin (L-PRF) as a local sustained released device for antibiotics.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Evaluation of leukocyte-platelet rich fibrin as an antibiotic slow-release biological device in the treatment of moderate periodontitis: a randomized controlled clinical trial.
Omar YK, Rashidy MAE, Ahmed GB, Aboulela AG. · · 2024 · cited 5× · PMID 39709402 · DOI 10.1186/s12903-024-05254-x

Verify or expand the search:

Other recruiting trials for Periodontitis

Currently open trials in the same condition.

NCT07463859 — Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabet · NA · recruiting
NCT07535177 — Gas6 and Soluble MerTK in Periodontal Diseases · recruiting
NCT07491848 — Oral-Periodontal Evaluation and Assessment of Oral Fluid Biomarkers in Patients With Hepatitis B+D · recruiting
NCT07421960 — Investigation of the Relationship Between Periodontitis and Sleep Quality · recruiting
NCT07532694 — Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06153706 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Yasmeen Khaled
Last refreshed: 1 December 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06153706.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing