NCT06150105: CHIPYA

Changes in the Hormonal and Inflammatory Profile of Young Sprint- and Endurance-trained Athletes.

Completed Last updated 6 December 2023

What this trial tests

trial testing Exercise training in Overtraining Syndrome in 24 participants. Completed in 10 December 2018.

Timeline

16 February 2018

Primary endpoint
24 February 2018

10 December 2018

Quick facts

Lead sponsor	Poznan University of Physical Education
Status	Completed
Study type	OBSERVATIONAL
Enrollment	24
Start date	16 February 2018
Primary completion	24 February 2018
Estimated completion	10 December 2018
Sites	1 location across Poland

Drugs / interventions tested

• Exercise training

Conditions studied

• Overtraining Syndrome — all drugs for Overtraining Syndrome →

Sponsor

Poznan University of Physical Education

Who can join

Adults 15 to 17, any sex, with Overtraining Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

One essential element of athlete training is conditioning camps, where athletes undergo a rigorous and targeted training schedule to prepare for upcoming sporting events. During sports camps, due to the accumulation of a large number of training units, including high-intensity exercises, athletes react with post-exercise overload, acute fatigue, and overreaching which can become a chronic overtraining syndrome. Overtraining syndrome is a very specific and severe condition where overtraining without adequate rest and recovery leads to performance decrements lasting more than 2-3 months, coupled with a mood disturbance. The exact etiology and pathogenesis are unknown and actively being investigated.

During training camps the balance between training volumes and recovery is often a delicate one and, the accumulation of exercise-induced stress may exceed the capacity of both neuroendocrine and immune adaptation leading to an alteration of physiological functions, decreasing adaptation to performance, impairment of psychological processing, immunological dysfunction, and biochemical abnormalities. Moreover, there is currently a lack of biomarkers accessible to assist in diagnosing and, what's even more important - help to prevent the overtraining syndrome, except for the continued presence of unexplained underperformance despite athletes' adequate rest and recovery.

Thus, this study aims to explain how long and intensive training for endurance affects the hormonal and immune systems of young athletes.

The main questions it aims to answer are:

1. How does intense training influence hormonal and immune responses in young, trained athletes?
2. Does training specialization affect the hormonal and immune response to intense training?

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Changes in the hormonal and inflammatory profile of young sprint- and endurance-trained athletes following a sports camp: a nonrandomized pretest-posttest study.
   Ostapiuk-Karolczuk J, Kasperska A, Dziewiecka H, Cieślicka M, et al · · 2024 · cited 2× · PMID 38898468 · DOI 10.1186/s13102-024-00924-3