NCT06148597

Effects of M-TAPA Block on Pulmonary Functions

Completed Last updated 22 April 2025

What this trial tests

trial testing Modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) in Pulmonary Functions in 1 participant. Completed in 1 July 2024.

Timeline

1 December 2023

Primary endpoint
30 May 2024

1 July 2024

Quick facts

Lead sponsor	Zonguldak Bulent Ecevit University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	1
Start date	1 December 2023
Primary completion	30 May 2024
Estimated completion	1 July 2024
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• Modified thoracoabdominal nerves block through perichondrial approach (M-TAPA)

Conditions studied

• Pulmonary Functions — all drugs for Pulmonary Functions →
• Pain Management — all drugs for Pain Management →
• Obesity, Morbid — all drugs for Obesity, Morbid →

Sponsor

Zonguldak Bulent Ecevit University

Who can join

Adults 18 to 65, any sex, with Pulmonary Functions or Pain Management. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Adequate postoperative analgesia is difficult to achieve in patients undergoing laparoscopic sleeve gastrectomy (LSG). Epidural anesthesia is technically difficult due to subcutaneous fat, which increases the risk of serious complications. Moreover, patients in this condition often have comorbidities that require anticoagulation therapy. Although ultrasound-guided Transversus Abdominis Plane (TAP) block may be useful, it is still controversial.

Recently, modified thoracoabdominal nerve block via perichondrial approach (M-TAPA) has been reported as a new and promising technique that provides effective analgesia in the anterior and lateral thoracoabdominal wall.

The most common reason for hospitalization after laparoscopic surgery is pain after nausea and vomiting. In addition, superficial and tachypneic breathing resulting from the patient's inability to breathe deeply with pain causes closure of small airways and increase in intrapulmonary shunts, resulting in hypoxia. Postoperative pain management is important not only to prevent pain but also to reduce pulmonary complications that may occur due to changes in lung function and to reduce mortality and morbidity by controlling the stress response.

In this study, The investigators investigated the effect of modified thoracoabdominal nerve block via perichondrial approach (M-TAPA) on pulmonary function in patients undergoing laparoscopic bariatric surgery under general anesthesia.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Effects of Modified Thoracoabdominal Nerves Block Through Pericondrial Approach on Postoperative Pulmonary Functions in Laparoscopic Bariatric Surgery: A Randomized Controlled Study.
   Baytar Ç, Gürbüz Z, Köksal İncegül BG, Baytar MS, et al · · 2025 · cited 2× · PMID 40397027 · DOI 10.1007/s11695-025-07908-3