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NCT06148233
CSF1R PET Probe [18F]CSF-23 in Alzheimer's Disease Brain Imaging
NA trial testing [18F]CSF-23 in Positron Emission Tomography in 40 participants. Status unknown.
16 June 2024
Quick facts
| Lead sponsor | Huashan Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 40 |
| Start date | 15 September 2023 |
| Primary completion | 16 June 2024 |
| Estimated completion | 14 September 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- [18F]CSF-23
Conditions studied
- Positron Emission Tomography — all drugs for Positron Emission Tomography →
- Alzheimer Disease — all drugs for Alzheimer Disease →
- Neurodegenerative Diseases — all drugs for Neurodegenerative Diseases →
Sponsor
Huashan Hospital
Who can join
Adults 60 to 80, any sex, with Positron Emission Tomography or Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To explore the diagnostic value of \[18F\]CSF-23 brain imaging for CSF1R expression in Alzheimer's disease. PET imaging with this PET tracer was used to assess the role and expression of CSF1R in AD and to evaluate the level and safety of abnormal present imaging.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Biomarkers and therapeutic strategies targeting microglia in neurodegenerative diseases: current status and future directions.
Noh MY, Kwon HS, Kwon MS, Nahm M, et al · · 2025 · cited 24× · PMID 40640892 · DOI 10.1186/s13024-025-00867-4
Verify or expand the search:
- PubMed search for NCT06148233
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06148233 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Huashan Hospital
- Last refreshed: 28 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06148233.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing