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NCT06146855
Amnion Membrane Versus DFGG Using the Tunneling Technique in Management of Gingival Recession Defects.
NA trial testing Tunneling procedure with Amnion Membrane in Gingival Recession in 22 participants. Status unknown.
1 December 2024
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 22 |
| Start date | 5 February 2024 |
| Primary completion | 1 December 2024 |
| Estimated completion | 1 December 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Tunneling procedure with Amnion Membrane
- Tunneling procedure with De-epithelialized Free Gingival Graft
Conditions studied
- Gingival Recession — all drugs for Gingival Recession →
Sponsor
Cairo University
Who can join
Adults 18 to 60, any sex, with Gingival Recession. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Treatment of gingival recession is indicated mainly for esthetic reasons and keratinized tissue augmentation (Zucchelli and Mounssif, 2015). An array of surgical techniques has been proposed by the literature to cover gingival recession defects with well-documented successful outcomes. The selection of one technique over the other depends on many factors. Some of these factors are related to the gingival recession defect itself, others are related to the anatomy of the palatal fibromucosa, or related to the patient variabilities (Zucchelli and De Sanctis, 2000). Controversy exists in the literature regarding the patient morbidity after connective tissue graft harvesting. Inconclusive postulations have been made about the post-operative patient morbidity outcomes and root coverage outcomes when comparing connective tissue graft harvesting in comparison to allograft membranes used for root coverage. The use of connective tissue graft in combination with root coverage techniques remain the gold standard for root coverage procedures. The problem with the connective tissue graft is that harvesting a graft from the palate increases morbidity, needs an extra surgical site which is more traumatic for the patient, depends on the donor tissue which could be limited, increases surgical chair-time and needs increased surgical skills (Cortellini \& Pini Prato 2012). The rationale behind the use of amnion membrane is to avoid the morbidity inherent with connective tissue graft harvesting.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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- PubMed search for NCT06146855
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Related trials
Other recruiting trials for Gingival Recession
Currently open trials in the same condition.
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- NCT07158541 — Comparing TCAF and MTUN With Soft Tissue Grafting for Treating Single Recessions in the Premandible · NA · recruiting
- NCT07104019 — Biofiller and Gingival Phenotype Thickening · NA · recruiting
- NCT07291583 — Hyaluronic Acid With Connective Tissue Grafting for Gingival Recession · NA · active not recruiting
Other Cairo University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06146855 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 13 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06146855.
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