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NCT06146829

Machine Learning Models for Prediction of Acute Kidney Injury After Noncardiac Surgery

Completed Last updated 10 April 2024
What this trial tests

trial testing no intervention in Postoperative Acute Kidney Injury in 88,367 participants. Completed in 15 December 2023.

Timeline
27 November 2023
Primary endpoint
15 December 2023
15 December 2023

Quick facts

Lead sponsorRao Sun
StatusCompleted
Study typeOBSERVATIONAL
Enrollment88,367
Start date27 November 2023
Primary completion15 December 2023
Estimated completion15 December 2023
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Rao Sun

Who can join

18 and older, any sex, with Postoperative Acute Kidney Injury. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute kidney injury (AKI) is a common surgical complication characterized by a rapid decline in renal function. Patients with AKI are at an increased risk of developing chronic kidney disease and end-stage renal disease, which has been associated with an increased risk of morbidity, mortality and financial burdens. Identifying high-risk patients for postoperative AKI early can facilitate the development of preventive and therapeutic management strategies, and prediction models can be helpful in this regard. The goal of this retrospective study is to develop prediction models for postoperative AKI in noncardiac surgery using machine learning algorithms, and to simplify the models by including only preoperative variables or only important predictors.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Development of interpretable machine learning models for prediction of acute kidney injury after noncardiac surgery: a retrospective cohort study.
    Sun R, Li S, Wei Y, Hu L, et al · · 2024 · cited 13× · PMID 38445452 · DOI 10.1097/js9.0000000000001237

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Other trials of no intervention

Trials testing the same drug.

Other recruiting trials for Postoperative Acute Kidney Injury

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Trials by the same sponsor.

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