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NCT06145360
Evaluating the Efficacy and Safety of Empagliflozin Addition to Insulin and Oral Antidiabetic Medication (OAD) Regimen in Poorly Controlled Type 2 Diabetes and Obese Patient
Phase 4 trial testing Empagliflozin 10 MG in Glucose Metabolism Disorders in 150 participants. Completed in 1 March 2024.
1 March 2024
Quick facts
| Lead sponsor | SINA Health Education and Welfare Trust |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | single group |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 150 |
| Start date | 1 December 2023 |
| Primary completion | 1 March 2024 |
| Estimated completion | 1 March 2024 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Empagliflozin 10 MG — full drug profile →
- Insulin+Metformin+DPP4 inhibitor (DPP4I) — full drug profile →
Conditions studied
- Glucose Metabolism Disorders — all drugs for Glucose Metabolism Disorders →
- Diabetes Mellitus, Type 2 — all drugs for Diabetes Mellitus, Type 2 →
- Hypoglycemic Agents — all drugs for Hypoglycemic Agents →
- Empagliflozin — all drugs for Empagliflozin →
Sponsor
SINA Health Education and Welfare Trust — full company profile →
Who can join
Adults 20 to 70, any sex, with Glucose Metabolism Disorders or Diabetes Mellitus, Type 2. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The primary aim of this study is to assess the impact of incorporating Empagliflozin, an oral sodium-glucose co-transporter 2 (SGLT2) inhibitor, into the existing therapeutic regimen of Insulin+Metformin+Dipeptidyl peptidase 4 (DPP-4) inhibitors in poorly controlled type 2 diabetes mellitus (T2DM) patients. The study seeks to evaluate its effect on achieving glycemic goals in this patient population.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06145360
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other SINA Health Education and Welfare Trust trials
Trials by the same sponsor.
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- NCT06523907 — "Effectiveness of Basic Nursing Educational Interventions on Primary Healthcare Paramedics: A Quasi-Experimental Approac · NA · completed
- NCT06358846 — Effectiveness of Educational Intervention on Footcare Among Individuals Having Type 2 Diabetes at Slums of Karachi, Paki · NA · completed
- NCT06140108 — Empagliflozin vs Metformin on Metabolic Dysfunction in Polycystic Ovary Syndrome With or Without Comorbidity or Multimor · Phase 2, PHASE3 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06145360 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by SINA Health Education and Welfare Trust
- Last refreshed: 8 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06145360.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing