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NCT06145139: KIDNEY-PAGER

KIDNEY-PAGER: Analysis of Circulating Tumor DNA as a Biomarker in Renal Cancer - an Observational Trial

ENROLLING BY INVITATION Last updated 22 November 2023
What this trial tests

trial in Renal Cancer in 500 participants. Enrolling by invitation.

Timeline
1 June 2023
Primary endpoint
1 June 2028
1 June 2033

Quick facts

Lead sponsorUniversity of Aarhus
StatusENROLLING BY INVITATION
Study typeOBSERVATIONAL
Enrollment500
Start date1 June 2023
Primary completion1 June 2028
Estimated completion1 June 2033
Sites1 location across Denmark

Conditions studied

Sponsor

University of Aarhus

Who can join

18 and older, any sex, with Renal Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The overall aim of this observational study is to confirm that circulating tumor DNA (ctDNA) detected in plasma and or urine after intended curative treatment for renal cell carcinoma (RCC) can be applied in clinical practice as a marker of subclinical residual disease and risk of recurrence.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Japan society of clinical oncology position paper on appropriate clinical use of molecular residual disease (MRD) testing.
    Kobayashi S, Nakamura Y, Hashimoto T, Bando H, et al · · 2025 · cited 6× · PMID 39920551 · DOI 10.1007/s10147-024-02683-0
  2. KIDNEY-PAGER: analysis of circulating tumor DNA as a biomarker in renal cancer - an observational trial. Study protocol.
    Iisager L, Ahrenfeldt J, Keller AK, Nielsen TK, et al · · 2024 · cited 6× · PMID 38391290 · DOI 10.2340/1651-226x.2024.25581
  3. Current Status and Future Perspectives of Molecular Residual Disease Testing in Genitourinary Cancers.
    Kato T, Yajima S, Nakamura Y, Kobayashi S, et al · · 2025 · cited 2× · PMID 40955810 · DOI 10.1111/iju.70215
  4. Using ctDNA to Inform Adjuvant Therapy for Urologic Malignancies.
    Goradia R, Goodstein T, Sundi D, Sood A, et al · · 2026 · PMID 41976347 · DOI 10.3390/cancers18071121

Verify or expand the search:

Other recruiting trials for Renal Cancer

Currently open trials in the same condition.

Other University of Aarhus trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06145139.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing