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NCT06143397
Effect of TTNS and PNS on Neurogenic Overactive Bladder Symptoms in Female Patients With Multiple Sclerosis.
NA trial testing TTNS (Transcutaneous tibial nerve stimulation) in Multiple Sclerosis in 42 participants. Completed in 30 October 2025.
20 October 2025
Quick facts
| Lead sponsor | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 42 |
| Start date | 20 November 2023 |
| Primary completion | 20 October 2025 |
| Estimated completion | 30 October 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- TTNS (Transcutaneous tibial nerve stimulation)
- PNS (Parasacral nerve stimulation)
- Sham stimulation
- Behavioral treatment — full drug profile →
Conditions studied
- Multiple Sclerosis — all drugs for Multiple Sclerosis →
- Overactive Bladder Syndrome — all drugs for Overactive Bladder Syndrome →
Sponsor
Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Who can join
Adults 18 to 65, female only, with Multiple Sclerosis or Overactive Bladder Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to evaluate the use of transcutaneous tibial nerve stimulation (TTNS) and parasacral nerve stimulation (PSS) methods in the treatment of overactive bladder (OAB) symptoms in patients with Multiple Sclerosis (MS), including urination frequency, urgency, urinary incontinence, post-void residue, maximum micturition rate. To investigate the effect on parameters such as voiding volume and quality of life and to compare the final results between groups.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06143397
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization trials
Trials by the same sponsor.
- NCT07500285 — Yittrium-90(Y-90) Fibroblast Activation Protein Inhibitor (FAPI) Therapy in Patients With Non-Small Cell Lung Cancer (Ph · Phase 2 · not yet recruiting
- NCT07489794 — URINARY INCONTINENCE AND PELVIC FLOOR MUSCLE ACTIVITY IN MULTIPLE SCLEROSIS · recruiting
- NCT07390279 — Efficacy of Transcutaneous Pulsed Radiofrequency in Postherpetic Neuralgia · recruiting
- NCT07357922 — Serum Progesterone and Threatened Abortion During Lactation · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06143397 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
- Last refreshed: 4 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06143397.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing