Who is sponsoring NCT06142903?

NCT06142903 is sponsored by University of Pennsylvania.

What drugs are being tested in NCT06142903?

Interventions in NCT06142903: 7 versus 21 medically tailored meals per week.

What condition does NCT06142903 study?

NCT06142903 studies Heart Failure, Malnutrition.

Is NCT06142903 still recruiting?

NCT06142903 is currently completed. Last updated 20 February 2025.

Last reviewed 2025-02-20 · How we verify

NCT06142903

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparative Effectiveness of 7 Versus 21 Home-delivered Medically Tailored Meals to Improve Malnutrition Risk in Malnourished Patients With Heart Failure

Completed NA Last updated 20 February 2025

What this trial tests

NA trial testing 7 versus 21 medically tailored meals per week in Heart Failure in 46 participants. Completed in 1 February 2024.

Timeline

1 August 2022

Primary endpoint
1 February 2024

1 February 2024

Quick facts

Lead sponsor	University of Pennsylvania
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	supportive care
Enrollment	46
Start date	1 August 2022
Primary completion	1 February 2024
Estimated completion	1 February 2024
Sites	1 location across United States

Drugs / interventions tested

7 versus 21 medically tailored meals per week

Conditions studied

Heart Failure — all drugs for Heart Failure →
Malnutrition — all drugs for Malnutrition →

Sponsor

University of Pennsylvania

Who can join

Adults 18 to 90, any sex, with Heart Failure or Malnutrition. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This protocol is designed to compare the effectiveness of two dietary intervention doses for patients with heart failure (HF) and malnutrition risk or malnutrition at hospital discharge. This random order crossover design will provide evidence as to whether the provision of dinner meals alone versus all 3 daily meals to patients' homes is more effective at improving malnutrition risk score, and secondarily unplanned emergency department visits and readmissions.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The nutritional impact of 7 versus 21 home-delivered medically tailored meals in patients with heart failure and malnutrition risk: a random order crossover feeding trial (MEDIMEALS).
Compher C, Henstenburg JA, Aloupis M, Sun A, et al · · 2025 · cited 5× · PMID 40102963 · DOI 10.1186/s40795-025-01036-y

Verify or expand the search:

Other recruiting trials for Heart Failure

Currently open trials in the same condition.

NCT06118983 — Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF) · NA · recruiting
NCT07496372 — Efficacy and Safety of Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Injection (HiCM-188) in Advanced Heart · Phase 3 · recruiting
NCT07527156 — Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure · Phase 4 · recruiting
NCT07263035 — Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure · Phase 4 · recruiting
NCT07531966 — Vascular Complications After Kidney Transplantation · recruiting

Other University of Pennsylvania trials

Trials by the same sponsor.

NCT06081153 — Mechanistic Clinical Trial of PCSK9 Inhibition for AAA · EARLY_PHASE1 · not yet recruiting
NCT07415772 — Effect of cTBS on Startle and TMS-evoked BOLD · NA · not yet recruiting
NCT07489430 — DaxibotulinumtoxinA for Blepharospasm · Phase 2 · not yet recruiting
NCT07463131 — Negative Income Tax Trial · NA · not yet recruiting
NCT06645769 — Na-Phenylbutyrate VAscular Trial · EARLY_PHASE1 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06142903 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Pennsylvania
Last refreshed: 20 February 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06142903.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing