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NCT06142409
Effect of Enzyme-containing Lozenge on Dental Biofilm Formation, Composition and Functionality
NA trial testing Enzyme containing lozenge in Dental Biofilm Accumulation in 34 participants. Completed in 25 February 2024.
25 February 2024
Quick facts
| Lead sponsor | Novozymes A/S |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | quadruple |
| Primary purpose | supportive care |
| Enrollment | 34 |
| Start date | 17 August 2023 |
| Primary completion | 25 February 2024 |
| Estimated completion | 25 February 2024 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Enzyme containing lozenge
Conditions studied
- Dental Biofilm Accumulation — all drugs for Dental Biofilm Accumulation →
Sponsor
Novozymes A/S
Who can join
18 and older, any sex, with Dental Biofilm Accumulation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A double-blind, placebo-controlled randomized cross-over trial evaluating the effect of enzyme-containing lozenge on in vivo and in situ grown dental biofilm accumulation. The study includes two phases, one each for the investigation of in-vivo and in-situ grown dental biofilm
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06142409
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Enzyme containing lozenge
Trials testing the same drug.
- NCT05070507 — Effect of an Enzyme-containing Lozenge on Dental Biofilm in Healthy Individuals. · NA · completed
Other Novozymes A/S trials
Trials by the same sponsor.
- NCT07163637 — Effect of Limosilactobacillus Reuteri DSM 17648 in Healthy Adults Reporting Upper Gastrointestinal Discomfort · NA · recruiting
- NCT06107088 — Effect of a Combination of Lactase and L. Salivarius DSM 34078 in Individuals With Lactose Intolerance · NA · completed
- NCT07079683 — RCT: Enzyme Blend Toothpaste on Dental Biofilm Plaque Accumulation · NA · completed
- NCT05507021 — Effect of Lactobacillus Plantarum DSM 33464 on Blood Lead Levels in Young Women of Child-bearing Age · NA · completed
- NCT05579938 — Effect of Enzymes on Dental Biofilm Accumulation · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06142409 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Novozymes A/S
- Last refreshed: 3 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06142409.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing