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NCT06140628
A 28-day Clinical Study on Facial Skin Rejuvenation
NA trial testing Fotona4D Pro® treatment followed by daily use of formulations containing MLYAAT-1002® in Wrinkle in 37 participants. Completed in 8 April 2024.
7 November 2023
Quick facts
| Lead sponsor | Botanee Group Co., Ltd. |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 37 |
| Start date | 24 September 2023 |
| Primary completion | 7 November 2023 |
| Estimated completion | 8 April 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- Fotona4D Pro® treatment followed by daily use of formulations containing MLYAAT-1002®
- Fotona4D Pro® treatment followed by daily use of formulations without MLYAAT-1002®
Conditions studied
- Wrinkle — all drugs for Wrinkle →
- Skin Laxity — all drugs for Skin Laxity →
- Skin Manifestations — all drugs for Skin Manifestations →
- Skin — all drugs for Skin →
Sponsor
Botanee Group Co., Ltd.
Who can join
Adults 30 to 50, female only, with Wrinkle or Skin Laxity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical trial aims to learn about the efficacy of MLYAAT-1002® (a proprietary anti-aging complex, MLYAAT is short for "multi-layer anti-ageing technology" ) in female subjects who have newly received the rejuvenation treatment by comparing visual clinical scores, skin attributes measurement and image analysis.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Clinical Measurement of Transepidermal Water Loss.
Kundu D, Jayaraman A, Sen CK. · · 2026 · cited 4× · PMID 40476522 · DOI 10.1089/wound.2024.0148 -
Continuous Skin Rejuvenation by Combining Nonablative Fractional Laser With Daily Application of a Multibeneficial Composition Formulation: A Blinded Randomized Clinical Trial Study.
Zhang X, Ning M, Lin M, Tang Q, et al · · 2025 · PMID 40041776 · DOI 10.1002/hsr2.70423
Verify or expand the search:
- PubMed search for NCT06140628
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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- NCT06385171 — Assessing the Impact of Botulinum Toxin Type A on Facial Wrinkles: A Comprehensive Clinical Investigation · recruiting
- NCT06557434 — AV-23-001 AVAVA MIRIA Pilot Study · NA · active not recruiting
- NCT06202274 — Clinical Study to Evaluate the Safety and Efficacy of Candela Technology · NA · active not recruiting
Other Botanee Group Co., Ltd. trials
Trials by the same sponsor.
- NCT06891924 — A Clinical Study on Pre-operative Intervention With Products During Aesthetic Medicine · NA · not yet recruiting
- NCT06188338 — A 56-day Clinical Study on Facial Skin Rejuvenation · NA · completed
- NCT05908903 — A Clinical Study on the Improvement of Sleep Quality, Skin Condition and Life Status After Taking Sleep Aid Drinks · NA · completed
- NCT06274450 — A Clinical Study on the Improvement of Skin and Living Conditions After Drinking Rosa Roxburghii and Pomegranate Drinks · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06140628 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Botanee Group Co., Ltd.
- Last refreshed: 16 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06140628.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing