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NCT06140381
Strengthening in Sub-acute Stroke Survivors: A Randomized Controlled Trial
NA trial testing Eccentric training in Hemiparesis;Poststroke/CVA in 40 participants. Status unknown.
1 June 2024
Quick facts
| Lead sponsor | Clinique Du Parc de Belleville |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | health services research |
| Enrollment | 40 |
| Start date | 1 December 2023 |
| Primary completion | 1 June 2024 |
| Estimated completion | 1 October 2024 |
| Sites | 1 location across France |
Drugs / interventions tested
- Eccentric training
- Conventional therapy — full drug profile →
Conditions studied
- Hemiparesis;Poststroke/CVA — all drugs for Hemiparesis;Poststroke/CVA →
Sponsor
Clinique Du Parc de Belleville
Who can join
Adults 20 to 75, any sex, with Hemiparesis;Poststroke/CVA. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this study is to compare between Eccentric training and conventional therapy in sub-acute stroke survivors. The primary objective of this study is to evaluate improvements in gait speed after four months of ET in comparison to conventional therapy for patients with sub-acute stroke. Secondary objectives involve assessing: i) modifications in neuromuscular parameters of PF, ii) changes in muscle stiffness within PF during passive mobilization and active force generation, and iii) modifications in architectural parameters of PF.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Impact of a 2-Month Program of Eccentric Training on Plantar Flexor Structure and Function in Hemiparesis After Stroke.
Pradines M, Jabouille F, Baude M, Gracies JM, et al · · 2025 · PMID 41477062 · DOI 10.1016/j.arrct.2025.100496 -
Eccentric strengthening vs. conventional therapy in sub-acute stroke survivors: a randomized controlled trial.
Belghith K, Zidi M, Vincent L, Fedele JM, et al · · 2024 · PMID 39917437 · DOI 10.3389/fneur.2024.1398860
Verify or expand the search:
- PubMed search for NCT06140381
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Eccentric training
Trials testing the same drug.
- NCT06748560 — Effects of Neurodynamic Sliding Versus Eccentric Training on Lower Extremity Function, Strength and Proprioception in At · NA · completed
- NCT03186287 — Effectiveness of Eccentric and Concentric Strength Training in Patients With Subacromial Impingement Syndrome · NA · completed
Other recruiting trials for Hemiparesis;Poststroke/CVA
Currently open trials in the same condition.
- NCT06797154 — A Novel Wrist Wearable Sensor System to Promote Hemiparetic Upper Extremity Use in Subacute Stroke Survivors · NA · recruiting
- NCT05626894 — Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors · Phase 2 · recruiting
- NCT06230796 — Effects of Functional Electrical Stimulation Assisted Cycling in Patients With Hemiparesis After Stroke · NA · recruiting
- NCT06107010 — Effects of Atalante Exoskeleton on Gait Recovery in Non- or Poorly Ambulatory Patients With Hemiparesis in the Acute/Sub · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06140381 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Clinique Du Parc de Belleville
- Last refreshed: 20 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06140381.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing