NCT06138977 is a NA clinical trial of Powered prosthesis in Amputation, sponsored by University of Michigan.

Who is sponsoring NCT06138977?

NCT06138977 is sponsored by University of Michigan.

What drugs are being tested in NCT06138977?

Interventions in NCT06138977: Powered prosthesis.

What condition does NCT06138977 study?

NCT06138977 studies Amputation.

Is NCT06138977 still recruiting?

NCT06138977 is currently recruiting now. Last updated 13 February 2026.

Last reviewed 2026-02-13 · How we verify

NCT06138977

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Controlling Locomotion Over Continuously Varying Activities for Agile Powered Prosthetic Legs

Recruiting now NA Last updated 13 February 2026

What this trial tests

NA trial testing Powered prosthesis in Amputation in 40 participants. Currently enrolling.

Timeline

6 December 2023

Primary endpoint
30 January 2028

30 January 2028

Quick facts

Lead sponsor	University of Michigan
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	other
Enrollment	40
Start date	6 December 2023
Primary completion	30 January 2028
Estimated completion	30 January 2028
Sites	1 location across United States

Drugs / interventions tested

Powered prosthesis

Conditions studied

Amputation — all drugs for Amputation →

Sponsor

University of Michigan

Who can join

Adults 18 to 65, any sex, with Amputation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The overall goal of this project is to model human joint biomechanics over continuously-varying locomotion to enable adaptive control of powered above-knee prostheses. The central hypothesis of this project is that variable joint impedance can be parameterized by a continuous model based on measurable quantities called phase and task variables. This project will use machine learning to identify variable impedance functions from able-bodied data including joint perturbation responses across the phase/task space to bias the solution toward biological values.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The clinical effects of the Össur Power Knee with phase-based and default control during sitting, standing, and walking.
Best TK, Seelhoff CA, Wensman J, Gregg RD. · · 2025 · cited 1× · PMID 41024213 · DOI 10.1186/s12984-025-01729-2

Verify or expand the search:

Other recruiting trials for Amputation

Currently open trials in the same condition.

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NCT07265154 — Gait Training and Artificial Intelligence · NA · recruiting
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NCT07347561 — A Comparison of Myoelectric and Bionic Hands · recruiting
NCT07364266 — Analgesic Amputation for Algodystrophy: Feedback From a Case Series · active not recruiting

Other University of Michigan trials

Trials by the same sponsor.

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NCT07471646 — Effects of Ramadan Fasting With Exercise on Cardiometabolic Health · NA · not yet recruiting
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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06138977 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Michigan
Last refreshed: 13 February 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06138977.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing