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NCT06135701: COPD-DOPPLER
Femoral Artery Blood Flow During Rest and One-leg Knee Extensor Exercise in Patients With COPD
NA trial testing One-legged knee-extensor exercise with Doppler measurements in COPD in 32 participants. Completed in 12 January 2024.
12 January 2024
Quick facts
| Lead sponsor | Rigshospitalet, Denmark |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 32 |
| Start date | 21 November 2023 |
| Primary completion | 12 January 2024 |
| Estimated completion | 12 January 2024 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- One-legged knee-extensor exercise with Doppler measurements
Conditions studied
- COPD — all drugs for COPD →
- Healthy — all drugs for Healthy →
- Chronic Obstructive Pulmonary Disease — all drugs for Chronic Obstructive Pulmonary Disease →
Sponsor
Rigshospitalet, Denmark
Who can join
Adults 45 to 80, any sex, with COPD or Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Doppler ultrasound is generally considered to provide reliable femoral blood flow measurements between rest and exercise, and the blood flow response to exercise is widely believed to be reduced in patients with chronic obstructive pulmonary disease (COPD). However, the test-retest reliability of the method during one-leg knee extensor exercise has not previously been compared between matched healthy individuals.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Test-retest reliability of Doppler ultrasound-based leg blood flow assessments during exercise in patients with chronic obstructive pulmonary disease.
Mohammad M, Hartmann JP, Andersen AB, Hartmeyer HL, et al · · 2026 · cited 6× · PMID 39223728 · DOI 10.1113/ep092100
Verify or expand the search:
- PubMed search for NCT06135701
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Rigshospitalet, Denmark trials
Trials by the same sponsor.
- NCT07401368 — Clinicians' Trust in AI-Based Fetal Growth Estimates · NA · not yet recruiting
- NCT07442357 — The Per-procedural Antibiotic Prophylaxis in Patients Undergoing Transcatheter Aortic Valve Implantation Trial · NA · not yet recruiting
- NCT07528729 — Alcohol as a Modifiable Risk Factor for Atrial Fibrillation · NA · not yet recruiting
- NCT07511439 — Reversible Effects of Oral Contraceptive Removal on Serotonergic Neurotransmission · Phase 4 · not yet recruiting
- NCT07467187 — Invasive Home Ventilation in Denmark · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06135701 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rigshospitalet, Denmark
- Last refreshed: 19 January 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06135701.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing