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Effects of NT-0796 in Obese Participants at Risk of Cardiovascular Disease

NCT06129409 PHASE1 COMPLETED

This trial is a Randomized, Double-Blind (Sponsor-Open), Placebo-Controlled Study to Assess the Effect of NT-0796 on Inflammation in Obese Participants at Risk of Cardiovascular Disease. Participants will be admitted to an in-patient Clinical Research Unit on Day -1 and will be discharged on Day 30. The trial will include a 7-day out-patient safety follow-up period following the last dose of study treatment. For the first approximately 20 participants effect of food will be evaluated on the Pharmacokinetics of NT-0796. MRI's will be conducted in a subset of participants.

Details

Lead sponsorNodThera Limited
PhasePHASE1
StatusCOMPLETED
Enrolment67
Start dateTue Oct 10 2023 00:00:00 GMT+0000 (Coordinated Universal Time)
CompletionMon Apr 15 2024 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Interventions

Countries

United States