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NCT06126796

Urine-based Molecular Testing vs Cystoscopy for Surveillance of Nonmuscle Invasive Bladder Cancer (NMIBC)

Completed Last updated 23 January 2026
What this trial tests

trial testing CxBladder Monitor in Non-muscle Invasive Bladder Cancer in 107 participants. Completed in 8 September 2025.

Timeline
16 November 2023
Primary endpoint
8 September 2025
8 September 2025

Quick facts

Lead sponsorMayo Clinic
StatusCompleted
Study typeOBSERVATIONAL
Enrollment107
Start date16 November 2023
Primary completion8 September 2025
Estimated completion8 September 2025
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Mayo Clinic

Who can join

18 and older, any sex, with Non-muscle Invasive Bladder Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to evaluate patient-reported preference for urine based molecular testing (CxBladder Monitor) compared to cystoscopy for patients on surveillance for Nonmuscle Invasive Bladder Cancer (NMIBC). Urine based molecular testing involves noninvasive testing of a urine sample for biomarkers associated with disease recurrence. Cystoscopy is an examination of the bladder and urethra using a thin tube like instrument that is inserted into the urethra.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Urine-Based Approaches for Screening, Diagnosis, and Surveillance of Urothelial Carcinoma.
    Bilim V, Hoshi S. · · 2026 · PMID 41893002 · DOI 10.3390/jpm16030135

Verify or expand the search:

Other recruiting trials for Non-muscle Invasive Bladder Cancer

Currently open trials in the same condition.

Other Mayo Clinic trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06126796.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing