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NCT06126796
Urine-based Molecular Testing vs Cystoscopy for Surveillance of Nonmuscle Invasive Bladder Cancer (NMIBC)
trial testing CxBladder Monitor in Non-muscle Invasive Bladder Cancer in 107 participants. Completed in 8 September 2025.
8 September 2025
Quick facts
| Lead sponsor | Mayo Clinic |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 107 |
| Start date | 16 November 2023 |
| Primary completion | 8 September 2025 |
| Estimated completion | 8 September 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- CxBladder Monitor
- Cystoscopy
Conditions studied
- Non-muscle Invasive Bladder Cancer — all drugs for Non-muscle Invasive Bladder Cancer →
Sponsor
Mayo Clinic
Who can join
18 and older, any sex, with Non-muscle Invasive Bladder Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate patient-reported preference for urine based molecular testing (CxBladder Monitor) compared to cystoscopy for patients on surveillance for Nonmuscle Invasive Bladder Cancer (NMIBC). Urine based molecular testing involves noninvasive testing of a urine sample for biomarkers associated with disease recurrence. Cystoscopy is an examination of the bladder and urethra using a thin tube like instrument that is inserted into the urethra.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Urine-Based Approaches for Screening, Diagnosis, and Surveillance of Urothelial Carcinoma.
Bilim V, Hoshi S. · · 2026 · PMID 41893002 · DOI 10.3390/jpm16030135
Verify or expand the search:
- PubMed search for NCT06126796
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Non-muscle Invasive Bladder Cancer
Currently open trials in the same condition.
- NCT07206225 — A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer · Phase 1 · recruiting
- NCT06503614 — A Trial of Durvalumab (MEDI4736) Plus Monalizumab in Non-Muscle-Invasive Bladder Cancer · Phase 2 · recruiting
- NCT06632964 — A Clinical Trial Aimed at Assessing the Efficacy and Safety of VT-101 for the Treatment of Non-muscle Invasive Bladder C · Phase 1 · recruiting
- NCT07252297 — The Role of Universal Cancer Only Marker SIX6 in Diagnosing Non-Muscle Invasive Bladder Cancer · NA · active not recruiting
- NCT04165317 — A Study of Sasanlimab in People With Non-muscle Invasive Bladder Cancer · Phase 3 · active not recruiting
Other Mayo Clinic trials
Trials by the same sponsor.
- NCT07126548 — A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men · NA · not yet recruiting
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- NCT07169799 — Impact of Cryotherapy Spray (Tru-Freeze) for the Eradication of Gastric Antral Vascular Ectasia (ICE-GAVE) · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06126796 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
- Last refreshed: 23 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06126796.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing