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NCT06124690
Persistent Atrial Fibrillation Without the Evidence of Low-voltage Areas
NA trial testing Catheter ablation in Persistent Atrial Fibrillation in 150 participants. Participants enrolled and being followed up; not accepting new ones.
1 September 2025
Quick facts
| Lead sponsor | Robert Bosch Medical Center |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 150 |
| Start date | 1 September 2023 |
| Primary completion | 1 September 2025 |
| Estimated completion | 1 September 2025 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Catheter ablation
Conditions studied
- Persistent Atrial Fibrillation — all drugs for Persistent Atrial Fibrillation →
- Catheter Ablation — all drugs for Catheter Ablation →
- Low Voltage Areas — all drugs for Low Voltage Areas →
Sponsor
Robert Bosch Medical Center
Who can join
Adults 18 to 85, any sex, with Persistent Atrial Fibrillation or Catheter Ablation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
An effective therapy of persistent atrial fibrillation beyond pulmonary vein isolation remains unsatisfactory. Targeting endocardial low-voltage areas represents an approach of substrate modification. This prospective, randomized study investigated the efficacy of ablation of low-voltage areas versus PVI and additional linear ablations in patients with persistent atrial fibrillation in terms of single-procedure arrhythmia-free outcome and safety.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06124690
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Catheter ablation
Trials testing the same drug.
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- NCT06632925 — Utility of Analyzing Atrial Signal Electrograms in Patients with Atrial Fibrillation Using Next-Generation Ensite X Soft · active not recruiting
- NCT06556485 — Preventive Catheter Ablation for Ventricular arrhythmiaS in Patients With End-sTage Heart faiLure · NA · recruiting
- NCT06560047 — Danish Evaluation of Early Catheter Ablation for Atrial Fibrillation in Patients With Heart Failure · NA · recruiting
- NCT06182566 — Hybrid Persistent Atrial Fibrillation Ablation in Heart Failure · NA · withdrawn
Other recruiting trials for Persistent Atrial Fibrillation
Currently open trials in the same condition.
- NCT07298473 — Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sp · NA · recruiting
- NCT07535268 — REPRESENT-PF Registry · recruiting
- NCT07508618 — Study on the Prevention of Atrial Fibrillation Recurrence After Ablation by Qidong Yixin Granule · Phase 4 · recruiting
- NCT07116525 — A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter · NA · recruiting
- NCT07106970 — PVI Alone vs PVI and Linear Ablation for Persistent Atrial Fibrillation (PROMPT AF II) · NA · recruiting
Other Robert Bosch Medical Center trials
Trials by the same sponsor.
- NCT05251545 — Randomized Trial: High Power Short Duration Versus Ablation Index · NA · completed
- NCT04904224 — Diagnosis of Inflammatory Bowel Disease by Examining the Entire Bowel by Pan-intestinal Capsule Endoscopy · NA · unknown
- NCT03988504 — Impact of Predictive Genetic Testing · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06124690 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Robert Bosch Medical Center
- Last refreshed: 18 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06124690.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing