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Effect of Lidocaine on Hemodynamic Response and Postoperative Sore Throat
Postoperative sore throat (POST) is a common outcome of general anesthesia in patients who undergo endotracheal intubation, and the estimated risk varies between 14.4% and 62%. It is one of the most undesirable postoperative anesthesia complications and has a negative impact on patient satisfaction and quality. Mucosal damage, inflammation, and erosion caused by endotracheal intubation all contribute to the development of POST. Therefore, POST is a condition that requires prevention and improvement. In the study, patients will be divided into two groups. The investigators will include 100 patients undergoing surgery under general anesthesia. The first group will receive 150 mg of lidocaine HCl solution 5 minutes before endotracheal intubation, while the second group will receive sterile distilled water as the control group. Throat pain assessment will be conducted in patients at 2, 6, 12, and 24 hours after surgery.
Details
| Lead sponsor | Dr. Lutfi Kirdar Kartal Training and Research Hospital |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 100 |
| Start date | Fri Dec 01 2023 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sun Jun 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Postoperative Sore Throat
Interventions
- Lidocaine Hydrochloride
- Drug (Placebo)
Countries
Turkey (Türkiye)