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Investigating Orthobiologics After PRP and Photobiomodulation for Knee Osteoarthritis
This research assesses the effects that Photobiomodulation Therapy (PBMT) has on Intra-articular administered Plasma-Rich Platelet (PRP) injections for Knee Osteoarthritis (KOA) treatment through evaluations of synovial and serum inflammatory and reparative biomarkers. A comparison of Physical Therapy (PT) vs PT + PRP vs PT + PBMT vs PT + PRP + PBMT for KOA treatment is made. The relationship between self-reported pain and functionality and treatment mechanisms is analyzed along with an analysis of the intersectionality between participant self-reported pain and functionality and medicine markers across treatment groups. These aims seek to inform current treatment practices in treating KOA and returning Active-Duty Service Members to duty readiness.
Details
| Lead sponsor | Musculoskeletal Injury Rehabilitation Research for Operational Readiness |
|---|---|
| Phase | NA |
| Status | TERMINATED |
| Enrolment | 33 |
| Start date | Fri Oct 13 2023 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Thu Oct 10 2024 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Knee Osteoarthritis
Interventions
- Physical Therapy
- Platelet-Rich Plasma Injection
- Photobiomodulation Therapy
Countries
United States