Last reviewed · How we verify
NCT06121544
The Swedish BioFINDER - Preclinical AD Study
trial testing Plasma tau in Alzheimer Disease in 800 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | Skane University Hospital |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 800 |
| Start date | 1 April 2022 |
| Primary completion | 31 December 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across Sweden |
Drugs / interventions tested
- Plasma tau
- Plasma β-Amyloid 42/40 (Aβ42/Aβ40)
- Flutemetamol F18 Injection
- [18F]-RO6958948 Injection
- Magnetic resonance imaging (MRI)
Conditions studied
- Alzheimer Disease — all drugs for Alzheimer Disease →
- Mild Cognitive Impairment — all drugs for Mild Cognitive Impairment →
- Mild Dementia — all drugs for Mild Dementia →
Sponsor
Skane University Hospital
Who can join
Adults 50 to 80, any sex, with Alzheimer Disease or Mild Cognitive Impairment. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This research study aims to examine biomarkers of Alzheimer's disease (AD) as early as possible which could potentially be a screening tool for the general population. This observational study will take place at the Skåne University Hospital in Sweden. The study will enroll up to 600 cognitively healthy subjects aged 50 to 80 years with 3/4 having preclinical Alzheimer's disease. Recruitment and enrollment will be ongoing for 2-3 years, and subject participation will be lasting approximately 4 years. Disclosure of AD risk assessments will be an optional procedure.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A minimally invasive dried blood spot biomarker test for the detection of Alzheimer's disease pathology.
Huber H, Montoliu-Gaya L, Brum WS, Vávra J, et al · · 2026 · cited 1× · PMID 41491101 · DOI 10.1038/s41591-025-04080-0
Verify or expand the search:
- PubMed search for NCT06121544
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Alzheimer Disease
Currently open trials in the same condition.
- NCT07290387 — Tele-Savvy for Latino Caregivers · NA · recruiting
- NCT07178210 — Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease · NA · recruiting
- NCT07294885 — Deep Cervical LymphatIc-Venous Anastomosis for Alzheimer's Disease · NA · recruiting
- NCT06937229 — A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3) · Phase 3 · recruiting
- NCT06930560 — HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms · NA · recruiting
Other Skane University Hospital trials
Trials by the same sponsor.
- NCT07426367 — Internet-Delivered ACT Targeting Emotional Distress and Chronic Pain · NA · not yet recruiting
- NCT06214988 — Selective Defunctioning Stoma in Low Anterior Resection for Rectal Cancer · NA · recruiting
- NCT06414382 — PSODEEP2 Pilot Study on Koebner Induction in Psoriasis · NA · not yet recruiting
- NCT06153303 — Internet-based ACT for Endometriosis and Chronic Pain · NA · recruiting
- NCT06122415 — The Swedish BioFINDER - Memory Clinic Study · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06121544 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Skane University Hospital
- Last refreshed: 6 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06121544.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing