NCT06120725 is a Phase 3 clinical trial of Ticagrelor 90 MG in Ischemic Stroke, sponsored by Kafrelsheikh University.

Who is sponsoring NCT06120725?

NCT06120725 is sponsored by Kafrelsheikh University.

What drugs are being tested in NCT06120725?

Interventions in NCT06120725: Ticagrelor 90 MG, Clopidogrel.

What condition does NCT06120725 study?

NCT06120725 studies Ischemic Stroke.

Is NCT06120725 still recruiting?

NCT06120725 is currently completed. Last updated 29 December 2023.

Last reviewed 2023-12-29 · How we verify

NCT06120725

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Ticagrelor Versus Clopidogrel in Large Vessel Ischemic Stroke

Completed Phase 3 Last updated 29 December 2023

What this trial tests

Phase 3 trial testing Ticagrelor 90 MG in Ischemic Stroke in 580 participants. Completed in 1 November 2023.

Timeline

1 September 2021

Primary endpoint
1 September 2023

1 November 2023

Quick facts

Lead sponsor	Kafrelsheikh University
Phase	Phase 3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	580
Start date	1 September 2021
Primary completion	1 September 2023
Estimated completion	1 November 2023
Sites	1 location across Egypt

Drugs / interventions tested

Ticagrelor 90 MG — full drug profile →
Clopidogrel (clopidogrel) — full drug profile →

Conditions studied

Ischemic Stroke — all drugs for Ischemic Stroke →

Sponsor

Kafrelsheikh University

Who can join

Adults 18 to 75, any sex, with Ischemic Stroke. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Along with the current clinical trial, the efficacy and safety of 180 mg loading dose of ticagrelor administered within 24 hours of first-ever large-vessel ischemic stroke compared to 300 mg clopidogrel were assessed through NIHSS, mRS, and possible adverse effects.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Ticagrelor Versus Clopidogrel in Acute Large-Vessel Ischemic Stroke: A Randomized Controlled Single-Blinded Trial.
Zeinhom MG, Elbassiouny A, Mohamed AM, Ahmed SR. · · 2024 · cited 10× · PMID 38619649 · DOI 10.1007/s40263-024-01080-5

Verify or expand the search:

Other trials of Ticagrelor 90 MG

Trials testing the same drug.

NCT06591338 — Combining Aspirin With Ticagrelor or Clopidogrel in Large-vessel Minor Stroke or TIA · Phase 3 · recruiting
NCT06561867 — Ticagrelor Versus Cilostazol in Ischemic Stroke · Phase 3 · recruiting
NCT06591377 — Combining Aspirin With Ticagrelor or Cilostazol in Large-vessel Minor Stroke or TIA · Phase 3 · recruiting
NCT06509893 — Ticagrelore Alone Post PCI · Phase 4 · recruiting
NCT06202755 — Ticagrelor Versus Cilostazol in Large-vessel Ischemic Stroke · Phase 3 · recruiting

Other recruiting trials for Ischemic Stroke

Currently open trials in the same condition.

NCT07509645 — Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Post · Phase 3 · recruiting
NCT07375953 — Repeated Intravenous Thrombolysis for Ischemic Stroke Within 3.0 Hours of Onset With Tenecteplase (RITIS-TNK) · Phase 2 · recruiting
NCT07375966 — Repeated Intravenous Thrombolysis for Ischemic Stroke With Medium to Large Vessel Occlusion Presenting Within 4.5 Hours · Phase 2 · recruiting
NCT07491952 — Continuous Dual Aspiration Technique With Zoom System for Stroke · recruiting
NCT07371455 — A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LWP779 in Healthy Participants · Phase 1 · recruiting

Other Kafrelsheikh University trials

Trials by the same sponsor.

NCT07585396 — Inositol in Letrozol Resistant PCOS Women · Phase 2, PHASE3 · not yet recruiting
NCT07433920 — L-PRF Versus Sticky Bone Grafting of the Jumping Gap in AI-assisted Computer-Guided Socket Shield Immediate Implantation · NA · recruiting
NCT07368348 — Evaluation of Internal Nasal Splint-Supported Free Graft Versus Nasoseptal Flap for Endoscopic Skull Base Repair in Cere · NA · recruiting
NCT07348094 — Guided Lateral Sinus Lifting Using Autologous Serum Albumin/Platelet-Rich Fibrin · NA · recruiting
NCT07359144 — Pilates Exercises on Nonspecific Low Back Pain in Postnatal Women · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06120725 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Kafrelsheikh University
Last refreshed: 29 December 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06120725.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing