Last reviewed · How we verify
NCT06117670
Gamma-irradiated Amniotic Membrane Graft in Posterior Colporrhaphy
Phase 3 trial testing posterior colporrhaphy using gamma-irradiated amniotic membrane as a graft in Rectocele; Female in 25 participants. Completed in 5 August 2025.
5 January 2025
Quick facts
| Lead sponsor | Ain Shams Maternity Hospital |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 25 |
| Start date | 1 November 2023 |
| Primary completion | 5 January 2025 |
| Estimated completion | 5 August 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- posterior colporrhaphy using gamma-irradiated amniotic membrane as a graft
Conditions studied
- Rectocele; Female — all drugs for Rectocele; Female →
- Pelvic Organ Prolapse — all drugs for Pelvic Organ Prolapse →
Sponsor
Ain Shams Maternity Hospital
Who can join
Adults 30 to 60, female only, with Rectocele; Female or Pelvic Organ Prolapse. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to test the benefit of using gamma-irradiated amniotic membrane as a graft in surgical repair for women with posterior vaginal wall defects. The main question it aims to answer is: • Is posterior colporrhaphy using gamma-irradiated amniotic membrane as a graft effective? Participants will undergo posterior colporrhaphy, which will be modified by adding gamma-irradiated amniotic membrane as a graft during the repair.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06117670
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Rectocele; Female
Currently open trials in the same condition.
- NCT07375147 — Transanal vs Transvaginal Rectal Resection for Anterior Rectocele · NA · recruiting
Other Ain Shams Maternity Hospital trials
Trials by the same sponsor.
- NCT07514078 — Evaluation of Laparoscopic Staging Versus Staging Laparotomy for Early Stage Endometrial Cancer · NA · not yet recruiting
- NCT07308977 — Practice of Assisted Vaginal Birth in Egypt · not yet recruiting
- NCT06935422 — Role of Cerebroplacental Ratio Discordance at 16-20 Weeks in Predicting Monochorionic Twin Pregnancies' Specific Complic · recruiting
- NCT06524700 — Pectopexy Autologous Vs Mesh · NA · active not recruiting
- NCT07247851 — Title of the Protocol: Combined Use of Vaginal Clindamycin Cream and Oral Metronidazole Versus Oral Metronidazole · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06117670 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams Maternity Hospital
- Last refreshed: 2 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06117670.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing