Last reviewed · How we verify
NCT06114888: PRESTO-1
Optimizing Care for Children Hospitalized With Community-acquired Pneumonia: Novel Diagnostics
NA trial testing MeMed BV + Usual Care in Community-acquired Pneumonia in 75 participants. Currently enrolling.
30 November 2025
Quick facts
| Lead sponsor | Jeffrey |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 75 |
| Start date | 17 April 2024 |
| Primary completion | 30 November 2025 |
| Estimated completion | 1 January 2026 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- MeMed BV + Usual Care
- Usual Care Alone
Conditions studied
- Community-acquired Pneumonia — all drugs for Community-acquired Pneumonia →
Sponsor
Jeffrey — full company profile →
Who can join
Adults 6 Months to 18, any sex, with Community-acquired Pneumonia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Children are commonly hospitalized because of community-acquired pneumonia. Despite the fact that many of these children have viral disease, a majority is treated with antibiotics. These antibiotics will not accelerate recovery in those with viral pneumonia and can cause harm. We are interested in exploring whether the MeMed BV - a composite biomarker assay - could be used to improve antibiotic prescribing in these children by identifying those who likely have viral disease. This proposal describes a feasibility randomized trial of this diagnostic intervention.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Diagnostic accuracy of MMBV in predicting bacterial infection in febrile children: a systematic review and meta-analysis.
Brigadoi G, Visentin D, Casotto V, Oteri C, et al · · 2026 · PMID 41514352 · DOI 10.1186/s13052-025-02185-3
Verify or expand the search:
- PubMed search for NCT06114888
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Community-acquired Pneumonia
Currently open trials in the same condition.
- NCT07164131 — Azithromycin Versus Doxycycline in Hospitalized Adult Patients With Community Acquired Pneumonia Treated With Beta-lacta · Phase 4 · recruiting
- NCT06577558 — Efficacy and Safety of SR1375 in Adult Patients With CAP · Phase 2 · recruiting
- NCT06229288 — Amoxicillin Alone Versus Amoxicillin/Clavulanate for Community-acquired Pneumonia in Patients Aged 65 Years or Older, an · Phase 3 · recruiting
- NCT06125340 — Optimizing Care for Children Hospitalized With Community-acquired Pneumonia: Short-course Therapy · Phase 4 · recruiting
- NCT06294600 — Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT) · Phase 3 · recruiting
Other Jeffrey trials
Trials by the same sponsor.
- NCT06125340 — Optimizing Care for Children Hospitalized With Community-acquired Pneumonia: Short-course Therapy · Phase 4 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06114888 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jeffrey
- Last refreshed: 10 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06114888.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing