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NCT06109922
Investigating the Effects of Dietary Phospholipids on Stress Reactivity and Recovery
NA trial testing Active in Mood in 150 participants. Completed in 20 January 2025.
20 December 2024
Quick facts
| Lead sponsor | Northumbria University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | other |
| Enrollment | 150 |
| Start date | 2 January 2024 |
| Primary completion | 20 December 2024 |
| Estimated completion | 20 January 2025 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Active (active) — full drug profile →
- Placebo
Conditions studied
- Mood — all drugs for Mood →
- Stress — all drugs for Stress →
- Physiological Stress — all drugs for Physiological Stress →
Sponsor
Northumbria University
Who can join
Adults 25 to 49, any sex, with Mood or Stress. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of the study is to investigate the effects of 6- and 12- week supplementation of a bioactive whey protein concentrate drink containing dairy phospholipids on stress reactivity and recovery in healthy adults. The proposed randomised, double-blind, placebo-controlled parallel groups design methodology will assess the stress reactivity and recovery effects (both self-reported and physiological) of 40g per day of bioactive whey protein concentrate in the form of a powder that the participant will be required to mix with 350ml of water and matched placebo prior to (baseline) and after -6 week and -12 week supplementation. The trial will utilise the Multi-tasking framework (MTF) during testing visits to elicit an acute stress response within the laboratory. Self reported anxiety (STAI short-form) at multiple time points before and after the stressor will be measured as well as perceived task demand following the stressor (NASA-TLX). Physiological measurements of the stress response will also be measured through blood pressure, heart rate arability, and galvanic skin response. 150 participants will participate, aged 25-49, and self-reported as being in good health. Participants will be supplied with either the active treatment or the placebo (allocated by a randomised schedule) whilst visiting the research centre for the testing appointments, and will take treatment home to consume daily for the duration of the study. Participants will record time of taking treatment each day in a treatment diary which will be returned to the research centre, along with any unused treatment, upon completion of the study.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06109922
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Other Northumbria University trials
Trials by the same sponsor.
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- NCT07242430 — 12-week Multi-vitamin/Mineral Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being · NA · not yet recruiting
- NCT07235878 — 12-week Magnesium Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being · NA · not yet recruiting
- NCT07297485 — Evaluating the Level of Agreement Between Goniometer Measurements and Algorithm to Determine Wall Squat Position · completed
- NCT06967454 — Manipulation of Whey Permeate Formulation for Better Fluid Retention. · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06109922 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Northumbria University
- Last refreshed: 11 September 2025
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