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NCT06104943: STRIREG

Stockholm hyperTRIglyceridemia REGister (STRIREG) Study

Active, enrolled Last updated 27 October 2023
What this trial tests

trial testing Heredity for cardiovascular disease in Familial Hypertriglyceridemia in 3,607,819 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline
1 January 2000
Primary endpoint
31 December 2021
31 December 2027

Quick facts

Lead sponsorRegion Stockholm
StatusActive, enrolled
Study typeOBSERVATIONAL
Enrollment3,607,819
Start date1 January 2000
Primary completion31 December 2021
Estimated completion31 December 2027

Drugs / interventions tested

Conditions studied

Sponsor

Region Stockholm — full company profile →

Who can join

Eligibility, any sex, with Familial Hypertriglyceridemia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The STRIREG study is a retrospective longitudinal general population-based register study including all individuals who had had at least one plasma Tg measurement between 1st January 2000 and 31st December 2021 at Karolinska University Laboratory or Unilabs AB in Region Stockholm (population 2.41 million 2021). The exclusion criteria were a lack of a unique Swedish personal identification number (PIN). The index population consisted of 1,460,184 individuals between the age 0 and 107 years. The index population was extended to form the complete cohort (n=3,607,819) by associating the parents and the siblings (n=2,147,635) to the indexes by interlinkage of personal identification numbers via the Multi-Generation register (see below). The study baseline for the index population was defined as the date for participant's first Tg measurement.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Relation among hypertriglyceridaemia, cardiometabolic disease, and hereditary factors-design and rationale of the Stockholm hyperTRIglyceridaemia REGister study.
    Andersson DP, Littmann K, Kindborg G, Eklund D, et al · · 2024 · cited 2× · PMID 38487365 · DOI 10.1093/ehjopen/oeae010

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Data sources for this page

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