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NCT06101940
A Multicenter Phenotype-Genotype Analysis of DM1 Patients in China
trial testing MRI scan in Myotonic Dystrophy 1 in 500 participants. Enrolling by invitation.
1 August 2030
Quick facts
| Lead sponsor | Huashan Hospital |
|---|---|
| Status | ENROLLING BY INVITATION |
| Study type | OBSERVATIONAL |
| Enrollment | 500 |
| Start date | 1 August 2021 |
| Primary completion | 1 August 2030 |
| Estimated completion | 30 December 2032 |
| Sites | 22 locations across China |
Drugs / interventions tested
- MRI scan
- Electrocardiography
- Pulmonary function test
Conditions studied
- Myotonic Dystrophy 1 — all drugs for Myotonic Dystrophy 1 →
Sponsor
Huashan Hospital
Who can join
Adults 18 to 80, any sex, with Myotonic Dystrophy 1. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Myotonic dystrophy 1 (DM1) is an autosomal, dominantly inherited neuromuscular disorder characterized by skeletal muscle weakness, myotonia, cardiac conduction abnormalities, cataracts, and other abnormalities. This disease results from an expansion of a cytosine-thymine-guanine (CTG) trinucleotide repeat in the 3'-untranslated region of the dystrophia myotonica protein kinase (DMPK) gene on chromosome 19. Currently, there is limited phenotype and genotype data available for DM1 patients with Chinese Han ethnicity. Therefore, this study aims to fill this gap and provide complementary data.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Clinical features and genetic spectrum of a multicenter Chinese cohort with myotonic dystrophy type 1.
Zhong H, Zeng L, Yu X, Ke Q, et al · · 2024 · cited 2× · PMID 38454488 · DOI 10.1186/s13023-024-03114-z
Verify or expand the search:
- PubMed search for NCT06101940
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Myotonic Dystrophy 1
Currently open trials in the same condition.
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Other Huashan Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06101940 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Huashan Hospital
- Last refreshed: 16 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06101940.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing