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NCT06099938

Effect of Different Labour Analgesics on Maternal and Fetal Blood Flow Observed by Doppler Ultrasonography

Completed Last updated 25 October 2023
What this trial tests

trial testing sufentanil, ropivacaine in Labor Pain in 90 participants. Completed in 1 January 2022.

Timeline
1 March 2021
Primary endpoint
1 December 2021
1 January 2022

Quick facts

Lead sponsorFirst Affiliated Hospital of Jinan University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment90
Start date1 March 2021
Primary completion1 December 2021
Estimated completion1 January 2022
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

First Affiliated Hospital of Jinan University

Who can join

Adults 20 to 35, female only, with Labor Pain or Analgesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: The purpose of this study was to see how intrathecal injections of sufentanil, ropivacaine, and sufentanil added to ropivacaine affected blood flow in the uterine artery, umbilical artery, and middle cerebral artery for combined spinal and epidural labor analgesia using color doppler ultrasound (CDUs). Methods: A total of 90 singleton full-term parturients who were evaluated by obstetricians for feasible vaginal delivery were collected prospectively and divided into three groups based on the randomization and double-blind principle: sufentanil (S), ropivacaine (R) group, each with 30 cases. Main indicators include color doppler blood flow resistance indices (S/D) of the uterine artery (UtA), umbilical artery (UA), and middle cerebral artery (MCA) before (T0) and 30 minutes (T1), 60 minutes (T2), 90minutes (T3) after analgesia. Fetal heart rate (FHR), maternal mean arterial pressure (MAP) at T0, T1, T2 and T3。

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Labor Pain

Currently open trials in the same condition.

Other First Affiliated Hospital of Jinan University trials

Trials by the same sponsor.

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Data sources for this page

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