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NCT06099626

Study of Clinical Features of Patients With Autoimmune Liver Disease Complicated With Covid-19 and the Immune Mechanism Affecting Prognosis

Status unknown Last updated 25 October 2023
What this trial tests

trial testing Different types of disease in Autoimmune Liver Disease, COVID-19 in 200 participants. Status unknown.

Timeline
1 January 2023
Primary endpoint
30 June 2024
30 December 2024

Quick facts

Lead sponsorThe Second Affiliated Hospital of Chongqing Medical University
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment200
Start date1 January 2023
Primary completion30 June 2024
Estimated completion30 December 2024
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

The Second Affiliated Hospital of Chongqing Medical University

Who can join

Eligibility, any sex, with Autoimmune Liver Disease, COVID-19. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

With the decreasing virulence of omicrons strain, the current domestic epidemic prevention policy has been changed based on the health of the people and the development needs of the country. At present, the infection rate of the novel coronavirus in China is rising rapidly. Previous studies have found that patients with chronic liver disease are more likely to be co-infected with coronavirus disease 2019 and have a worse prognosis. Based on its unique immune mechanism and therapeutic drugs, patients with autoimmune liver disease also have very different manifestations after infection with the novel coronavirus. By observing the clinical characteristics and prognosis of patients with autoimmune liver disease complicated with coronavirus disease 2019, this study analyzed the roles of vaccines, immunosuppressive agents and ursodeoxycholic acid , and explored the immune mechanism behind them, so as to seek new anti-coronavirus disease 2019 drugs and provide new strategies for clinical prevention and treatment.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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