NCT06099171 is a Phase 3 clinical trial of Cannabidiol and β-Caryophyllene Patch in Neck Pain, sponsored by Humanitas Clinical and Research Center.

Who is sponsoring NCT06099171?

NCT06099171 is sponsored by Humanitas Clinical and Research Center.

What drugs are being tested in NCT06099171?

Interventions in NCT06099171: Cannabidiol and β-Caryophyllene Patch, Oxygen-Ozone Therapy.

Is NCT06099171 still recruiting?

NCT06099171 is currently status unknown. Last updated 13 December 2023.

Last reviewed 2023-12-13 · How we verify

NCT06099171

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Therapy With Paravertebral Oxygen-ozone Injections and Topical Cannabidiol and β-Caryophyllene Patch in Neck Pain

Status unknown Phase 3 Last updated 13 December 2023

What this trial tests

Phase 3 trial testing Cannabidiol and β-Caryophyllene Patch in Neck Pain in 52 participants. Status unknown.

Timeline

1 February 2024

Primary endpoint
1 September 2024

1 March 2025

Quick facts

Lead sponsor	Humanitas Clinical and Research Center
Phase	Phase 3
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	52
Start date	1 February 2024
Primary completion	1 September 2024
Estimated completion	1 March 2025
Sites	1 location across Italy

Drugs / interventions tested

Cannabidiol and β-Caryophyllene Patch — full drug profile →
Oxygen-Ozone Therapy

Conditions studied

Neck Pain — all drugs for Neck Pain →

Sponsor

Humanitas Clinical and Research Center

Who can join

Adults 18 to 99, any sex, with Neck Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to compare the effectiveness of combined treatment with paravertebral oxygen-ozone injections and topical patches containing Cannabidiol and β-Caryophyllene in patients with neck pain by evaluating the following aspects: * Reduction of pain * Reduction of disability associated with neck pain

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Advancing Brain Health Naturally: β-Caryophyllene and Xanthohumol as Neuroprotective Agents.
Ivanova S, Dzhakova Z, Todorova V, Boyuklieva R, et al · · 2025 · cited 1× · PMID 41011595 · DOI 10.3390/molecules30183702

Verify or expand the search:

Other recruiting trials for Neck Pain

Currently open trials in the same condition.

NCT07163533 — Combined Effect of Kendall Exercises With Wearable Vibrotactile Feedback Sensor in Forward Head Posture · NA · recruiting
NCT07332845 — Symmetrical Scapula-pelvis Proprioceptive Neuromuscular Facilitation and Superficial Back Line in Chronic Neck Pain With · NA · recruiting
NCT07524075 — Effects of Muscle Energy Technique on Neck Disability and Cervical Range of Motion in Individuals With Non-Specific Neck · NA · recruiting
NCT07292350 — Investigation of the Effects of a Neuromuscular Control-Focused Posture Training Program in Butchers · NA · recruiting
NCT07290361 — Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT) · NA · recruiting

Other Humanitas Clinical and Research Center trials

Trials by the same sponsor.

NCT07161297 — Remimazolam for Colonoscopy in IBD Patients · Phase 4 · not yet recruiting
NCT04934943 — "Mini Fluid Challenge Assessment: a Comparison Among Three Hemodynamic Tools" · not yet recruiting
NCT06394947 — Fluid Challenge in Intensive Care The FENICE II Study · completed
NCT06627907 — Hemodynamic Response to the End-expiratory Occlusion Test to Titrate Fluid Challenge in Operating Room. · not yet recruiting
NCT06691061 — The PODIUM Study - a Three-arm Comparison of Target Therapies After Anti-TNFα in Ulcerative Colitis · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06099171 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Humanitas Clinical and Research Center
Last refreshed: 13 December 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06099171.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing