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NCT06097182: PIAS
Post-biotic Intervention for Acute Stress Management
NA trial testing Post-biotic (Colonic-Delivery capsule) in Stress Response in 75 participants. Completed in 14 June 2024.
14 June 2024
Quick facts
| Lead sponsor | Institute for Human Development and Potential (IHDP), Singapore |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | basic science |
| Enrollment | 75 |
| Start date | 1 November 2023 |
| Primary completion | 14 June 2024 |
| Estimated completion | 14 June 2024 |
| Sites | 1 location across Singapore |
Drugs / interventions tested
- Post-biotic (Colonic-Delivery capsule)
- Post-biotic (Regular Administration capsule)
- Placebo
Conditions studied
- Stress Response — all drugs for Stress Response →
- Mood State — all drugs for Mood State →
- Sleep — all drugs for Sleep →
- Cognition — all drugs for Cognition →
Sponsor
Institute for Human Development and Potential (IHDP), Singapore
Who can join
Adults 21 to 30, male only, with Stress Response or Mood State. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study aims to evaluate the sub-chronic effects of colonic delivery of a post-biotic on stress response, mood state, sleep, and cognition in healthy young subjects with elevated self-reported stress levels. It is hypothesized that oral intake of the post-biotic, when released in the colonic intestinal site, leads to a blunted subjective and objective stress response after a stress induction.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A Comprehensive Overview of Postbiotics with a Special Focus on Discovery Techniques and Clinical Applications.
Kumar A, Green KM, Rawat M. · · 2024 · cited 34× · PMID 39335866 · DOI 10.3390/foods13182937
Verify or expand the search:
- PubMed search for NCT06097182
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Stress Response
Currently open trials in the same condition.
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Other Institute for Human Development and Potential (IHDP), Singapore trials
Trials by the same sponsor.
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- NCT07100639 — Singapore Population Research on Integrated exposoMe & Early Menopause · not yet recruiting
- NCT06765889 — Mindfulness-Based Intervention for Stress Reduction in Adult Singaporeans a Pilot Study · NA · completed
- NCT06484543 — Brown Fat as Therapeutic Strategy for Obesity and Associated Metabolic Diseases Via Functional Food/Nutraceutical Approa · NA · active not recruiting
- NCT06147700 — Identifying Molecular Determinants of Infertility in Men (MODIFY) · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06097182 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Institute for Human Development and Potential (IHDP), Singapore
- Last refreshed: 16 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06097182.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing