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NCT06096376: ULTRAFLOW
Predictors of HFNC Failure in Patients With AHRF Using Diaphragm Ultrasound
trial testing Diaphragm Ultrasound in Acute Hypoxemic Respiratory Failure in 30 participants. Completed in 1 September 2024.
26 June 2024
Quick facts
| Lead sponsor | Queen Mary Hospital, Hong Kong |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 30 |
| Start date | 28 April 2023 |
| Primary completion | 26 June 2024 |
| Estimated completion | 1 September 2024 |
| Sites | 1 location across Hong Kong |
Drugs / interventions tested
- Diaphragm Ultrasound
Conditions studied
- Acute Hypoxemic Respiratory Failure — all drugs for Acute Hypoxemic Respiratory Failure →
Sponsor
Queen Mary Hospital, Hong Kong
Who can join
Adults 18 to 100, any sex, with Acute Hypoxemic Respiratory Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Ultrasound of the diaphragm is an easily reproducible bedside tool that provides a non-invasive measurement of inspiratory muscle function and respiratory efficiency. The diaphragmatic thickness correlates with the strength and muscle shortening and is reflective of its contribution to the respiratory workload. Diaphragm thickening fraction (DTF) has been shown to be predictive of extubation failure in ventilated patients. However, whether measurements of DTF are predictive of high flow nasal cannula (HFNC) outcomes in patients with acute hypoxemic respiratory failure (AHRF) remains unknown. The objective of this study is to identify predictors of HFNC failure by diaphragm ultrasound and to compare its performance with the well-established ROX index.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06096376
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Diaphragm Ultrasound
Trials testing the same drug.
- NCT07057804 — Lung and Diaphragm Ultrasound in Predicting Extubation and Weaning of Mechanically Ventilated Patients in Intensive Care · completed
- NCT05903001 — Diaphragmatic Function as a Biomarker · recruiting
- NCT03709199 — Long Term Follow up of Children Enrolled in the REDvent Study · active not recruiting
- NCT03266016 — Real-time Effort Driven VENTilator Management · NA · completed
Other recruiting trials for Acute Hypoxemic Respiratory Failure
Currently open trials in the same condition.
- NCT07334379 — Interleukin-6 Guided Treatment With Dexamethasone or Tocilizumab in Patients Hospitalized With Acute Respiratory Symptom · Phase 2 · recruiting
- NCT06921655 — Targeting prEssure-Muscle-index to Avoid Ventilatory Over-Assistance During Pressure Support Ventilation · NA · recruiting
- NCT06931938 — Awake Prone Positioning in Spontaneous Breathing Patients With Acute Hypoxic Respiratory Failure Due to Pneumonia · NA · recruiting
- NCT07178483 — Evaluation of Physical Capacity and Energy Requirements in Patients With Hypoxemic Acute Respiratory Failure · active not recruiting
- NCT06815523 — Prediction of Duration of Mechanical Ventilation in Acute Hypoxemic Respiratoty Failure · active not recruiting
Other Queen Mary Hospital, Hong Kong trials
Trials by the same sponsor.
- NCT07461064 — HIFU vs Observation for LSIL of Cervix: A Randomized Controlled Trial · NA · not yet recruiting
- NCT06178471 — Safety, Feasibility and Clinical Utility of Critical Care Transesophageal Echocardiography in Hong Kong · not yet recruiting
- NCT06037356 — PUL vs TURP in BPH Patients With Urinary Retention · NA · recruiting
- NCT06643416 — Efficacy and Safety of Add-on Timolol for EGFR-TKI and ALK-TKI Induced Paronychia · Phase 3 · recruiting
- NCT06551337 — Vitamin D Replacement in Bronchiectasis · Phase 4 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06096376 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Queen Mary Hospital, Hong Kong
- Last refreshed: 17 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06096376.
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