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NCT06095856
Evaluation of Masseter and Anterior Temporalis Muscles Activity After Locating Centric Relation
NA trial testing Leaf Gauge in Centric Occlusion - Centric Relation Discrepancy (Disorder) in 25 participants. Completed in 31 December 2023.
31 December 2023
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | other |
| Enrollment | 25 |
| Start date | 1 November 2023 |
| Primary completion | 31 December 2023 |
| Estimated completion | 31 December 2023 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Leaf Gauge
- Lucia Jig
- Kois Deprogrammer
Conditions studied
- Centric Occlusion - Centric Relation Discrepancy (Disorder) — all drugs for Centric Occlusion - Centric Relation Discrepancy (Disorder) →
Sponsor
Cairo University
Who can join
Adults 20 to 50, any sex, with Centric Occlusion - Centric Relation Discrepancy (Disorder). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Statement of the Problem: To create optimum maxillomandibular relationships, ease discomfort, and restore function, occlusal devices are used, therefore, these devices are of great importance in the field of prosthodontics. Literature is scarce regarding the effect of various methods used in locating centric relation on muscle activity, in addition to which method is most accepted by the patients for whom centric relation is being located. Null hypothesis: There will be no difference in Masseter and Anterior Temporalis muscles activity and patient satisfaction after using the Leaf Gauge, The Lucia Jig and the Kois Deprogrammer.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Anterior temporalis and masseter muscle activity with different centric relation locating methods: A randomized cross-over trial.
Nofal AT, Kois JC, Elbasty RS, Zaki AA. · · 2025 · PMID 41083874 · DOI 10.1038/s41598-025-21616-z
Verify or expand the search:
- PubMed search for NCT06095856
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06095856 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 9 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06095856.
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