Last reviewed · How we verify
NCT06093698: A-337
An Exploratory Study of A-337 in the Management of Malignant Solid Dose Escalation and Expansion Phases
Phase 1 trial testing Recombinant Anti-EpCAM-CD3 Antibody Injection in Recurrent or Metastatic Solid Tumors in 94 participants. Not yet recruiting.
30 June 2026
Quick facts
| Lead sponsor | ITabMed Co., Ltd. |
|---|---|
| Phase | Phase 1 |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 94 |
| Start date | 1 December 2023 |
| Primary completion | 30 June 2026 |
| Estimated completion | 31 December 2026 |
Drugs / interventions tested
- Recombinant Anti-EpCAM-CD3 Antibody Injection — full drug profile →
Conditions studied
- Recurrent or Metastatic Solid Tumors — all drugs for Recurrent or Metastatic Solid Tumors →
Sponsor
ITabMed Co., Ltd. — full company profile →
Who can join
Adults 18 to 75, any sex, with Recurrent or Metastatic Solid Tumors. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Title: An Exploratory Study of A-337 in the Management of Malignant Solid Dose Escalation and Expansion Phases
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Current landscape of T-cell engagers in early-phase clinical development in solid cancers.
Spinazzola A, Iannantuono GM, Gulley JL, Giudice E, et al · · 2025 · cited 3× · PMID 41122165 · DOI 10.3389/fimmu.2025.1665838
Verify or expand the search:
- PubMed search for NCT06093698
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Recurrent or Metastatic Solid Tumors
Currently open trials in the same condition.
- NCT07015697 — A Study of Subcutaneous Trastuzumab Deruxtecan in Participants With Metastatic Solid Tumors · Phase 1 · recruiting
- NCT06330064 — A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic So · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06093698 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by ITabMed Co., Ltd.
- Last refreshed: 23 October 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06093698.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing