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NCT06092853
Inflammatory Stress and Periodontal Tissue Destruction
trial testing Gingival crevicular fluid (GCF) and serum samples in Oxidative Stress in 80 participants. Completed in 6 June 2023.
6 March 2023
Quick facts
| Lead sponsor | Recep Tayyip Erdogan University Training and Research Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 80 |
| Start date | 6 June 2022 |
| Primary completion | 6 March 2023 |
| Estimated completion | 6 June 2023 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Gingival crevicular fluid (GCF) and serum samples
Conditions studied
- Oxidative Stress — all drugs for Oxidative Stress →
- Inflammation — all drugs for Inflammation →
Sponsor
Recep Tayyip Erdogan University Training and Research Hospital
Who can join
Adults 20 to 65, any sex, with Oxidative Stress or Inflammation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Metabolic syndrome and periodontitis are diseases that lower the quality of life and their incidence rates are increasing. Since both of these diseases are associated with systemic inflammation and insulin resistance, they may be comorbid. The aim of this study was to evaluate the effect of interleukin-20 (IL-20) on periodontal destruction in individuals with metabolic syndrome while considering the relationship between metabolic syndrome and periodontitis. This study included a total of 80 individuals who were systemically and periodontally healthy (CG, n=20), were systemically healthy and had periodontitis (PG, n=20), had metabolic syndrome and were periodontally healthy (MG, n=20), or had both metabolic syndrome and periodontitis (MPG, n=20). Gingival crevicular fluid (GCF) and serum samples were collected from all participants for biochemical analyses.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The role of interleukin-20 on inflammatory stress and periodontal tissue destruction in patients with metabolic syndrome and periodontitis.
Senkal R, Yemenoglu H, Kose O, Karakas SM, et al · · 2024 · PMID 39578819 · DOI 10.1186/s12903-024-05224-3
Verify or expand the search:
- PubMed search for NCT06092853
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Recep Tayyip Erdogan University Training and Research Hospital trials
Trials by the same sponsor.
- NCT07427095 — The Relationship Between Ultra-Processed Food Consumption and Oral Health · not yet recruiting
- NCT07427069 — Chronic Kidney Disease Associated Diet · not yet recruiting
- NCT07462104 — Metabolic Syndrome Associated Diet · not yet recruiting
- NCT07354815 — Metabolic Syndrome-Associated Periodontal Inflammatory Surface Area · not yet recruiting
- NCT07287540 — Anti-inflammatory Nutrition on the Outcomes of Non-surgical Periodontal Therapy · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06092853 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Recep Tayyip Erdogan University Training and Research Hospital
- Last refreshed: 23 October 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06092853.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing