NCT06092060 is a NA clinical trial of the group GS (probiotic) in Insulin Resistance, sponsored by Poznan University of Physical Education.

Who is sponsoring NCT06092060?

NCT06092060 is sponsored by Poznan University of Physical Education.

What drugs are being tested in NCT06092060?

Interventions in NCT06092060: the group GS (probiotic), the group GP (placebo).

What condition does NCT06092060 study?

NCT06092060 studies Insulin Resistance.

Is NCT06092060 still recruiting?

NCT06092060 is currently completed. Last updated 23 October 2023.

Last reviewed 2023-10-23 · How we verify

NCT06092060

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of a Multistrain Probiotic on Metformin Tolerance and Efficacy With Microbiota and Stool Metabolome in Insulin-resistant Women - a 12-week Randomized, Placebo-controlled, Double-blind Study

Completed NA Last updated 23 October 2023

What this trial tests

NA trial testing the group GS (probiotic) in Insulin Resistance in 40 participants. Completed in 20 July 2023.

Timeline

1 April 2021

Primary endpoint
1 February 2022

20 July 2023

Quick facts

Lead sponsor	Poznan University of Physical Education
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	40
Start date	1 April 2021
Primary completion	1 February 2022
Estimated completion	20 July 2023
Sites	1 location across Poland

Drugs / interventions tested

the group GS (probiotic)
the group GP (placebo)

Conditions studied

Insulin Resistance — all drugs for Insulin Resistance →

Sponsor

Poznan University of Physical Education

Who can join

Adults 25 to 45, female only, with Insulin Resistance. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this study is to evaluate the efficacy of metformin on insulin sensitivity and vascular endothelial function with respect to gut microbiota and metabolome in women with established insulin resistance and its tolerance after 12 weeks of probiotic therapy. The hypothesis is probiotic therapy in women with established insulin resistance undergoing metformin treatment increases the drug's efficacy to improve insulin sensitivity and intestinal endothelial function, and reduces gastrointestinal side effects. Study participants will be randomly assigned to 2 groups, taking a probiotic (GS) or a placebo (GP). The randomization scheme will be computer-generated using permuted blocks of block size 4.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Multi-strain probiotic reduces gastrointestinal side effects in women with elevated HOMA-IR index treated with metformin: a 12-week randomised controlled trial.
Ratajczak M, Bilska A, Musialik K, Skonieczna-Żydecka K, et al · · 2026 · cited 1× · PMID 41852479 · DOI 10.3389/fendo.2026.1765741

Verify or expand the search:

Other recruiting trials for Insulin Resistance

Currently open trials in the same condition.

NCT07403604 — Effect of Insulin Lowering on Lipogenesis · Phase 1 · recruiting
NCT07226128 — The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV · NA · recruiting
NCT07505745 — MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity · Phase 2 · recruiting
NCT07220694 — Effects of Sabroxy® Supplementation on Insulin Resistance and Cognitive Function in Adults With Mild Cognitive Impairmen · NA · recruiting
NCT06768827 — New Mechanisms of Obesity · NA · recruiting

Other Poznan University of Physical Education trials

Trials by the same sponsor.

NCT07437833 — Psychophysiological Responses to Six Single-Session Self-Regulation Interventions in a Female Adult With ADHD and Stabil · NA · not yet recruiting
NCT07379606 — Effects of Moderate Exercise and Cyclic Sighing on Stress, Cognition and Physiological Markers in Young Adults · NA · not yet recruiting
NCT07232836 — Cytokines, Neuroplasticity Modulators, and Biomarkers in Spinal Canal Stenosis and Endoscopic Decompression · NA · not yet recruiting
NCT06935058 — Effectiveness of Chocolate Milk in Recovery Among Highly Trained Kayakers: A Metabolic and Inflammatory Perspectives · NA · completed
NCT06926257 — Effects of VR-based Respiratory Training on Motor Reaction Time and Correctness, Stress Levels, Attention, Motor Skills, · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06092060 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Poznan University of Physical Education
Last refreshed: 23 October 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06092060.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing